Severe form of Legionnaires' disease in an immunocompetent patient
Background. Legionnaires' disease (LD) is a pneumonia caused by Legionella pneumophila (LP). The disease occurs more often in immunocompromised persons and can be manifested by severe pneumonia, multiple organ failure and has a high mortality. Case report. Immunocompetent patient, male, 53- yea...
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| Format: | Article |
| Language: | English |
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Military Health Department, Ministry of Defance, Serbia
2009-01-01
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| Series: | Vojnosanitetski Pregled |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/0042-8450/2009/0042-84500912010A.pdf |
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| author | Andrijević Ilija Matijašević Jovan Považan Đorđe Kojičić Marija Batranović Uroš |
| author_facet | Andrijević Ilija Matijašević Jovan Považan Đorđe Kojičić Marija Batranović Uroš |
| author_sort | Andrijević Ilija |
| collection | DOAJ |
| description | Background. Legionnaires' disease (LD) is a pneumonia caused by Legionella pneumophila (LP). The disease occurs more often in immunocompromised persons and can be manifested by severe pneumonia, multiple organ failure and has a high mortality. Case report. Immunocompetent patient, male, 53- year old, with severe form of LB had fever, cough, weakness and diarrhea as the initial symptoms of the disease. Laboratory results showed increased number of leukocytes, increased values of acute phase proteins, liver enzymes and hyponatremia. Computed tomography of the chest showed the marked inflammatory lesions on both sides. Pathohystological analysis of the samples retrieved by bronchoscopy pointed to a pneumonia, and diagnosis of LD was confirmed by positive urine test for LP antigen. Later, the disease was complicated by acute adult respiratory distress syndrome (ARDS). Treatment with antibiotics (erythromycin, rifampicin, azithromycin) combined with ARDS treatment led to a clinical recovery of the patient together with complete resolution of inflammatory lesions seen on chest radiography. Conclusion. In severe pneumonias it is necessary to consider LD in differential diagnosis, perform tests with aim of detecting LP and apply adequate antibiotic treatment in order to accomplish positive outcome of the therapy and prevent complications. |
| first_indexed | 2024-04-14T03:55:56Z |
| format | Article |
| id | doaj.art-00d07fb5f45d44eaa6b98b9f6098cfcb |
| institution | Directory Open Access Journal |
| issn | 0042-8450 |
| language | English |
| last_indexed | 2024-04-14T03:55:56Z |
| publishDate | 2009-01-01 |
| publisher | Military Health Department, Ministry of Defance, Serbia |
| record_format | Article |
| series | Vojnosanitetski Pregled |
| spelling | doaj.art-00d07fb5f45d44eaa6b98b9f6098cfcb2022-12-22T02:13:45ZengMilitary Health Department, Ministry of Defance, SerbiaVojnosanitetski Pregled0042-84502009-01-0166121010101410.2298/VSP0912010ASevere form of Legionnaires' disease in an immunocompetent patientAndrijević IlijaMatijašević JovanPovažan ĐorđeKojičić MarijaBatranović UrošBackground. Legionnaires' disease (LD) is a pneumonia caused by Legionella pneumophila (LP). The disease occurs more often in immunocompromised persons and can be manifested by severe pneumonia, multiple organ failure and has a high mortality. Case report. Immunocompetent patient, male, 53- year old, with severe form of LB had fever, cough, weakness and diarrhea as the initial symptoms of the disease. Laboratory results showed increased number of leukocytes, increased values of acute phase proteins, liver enzymes and hyponatremia. Computed tomography of the chest showed the marked inflammatory lesions on both sides. Pathohystological analysis of the samples retrieved by bronchoscopy pointed to a pneumonia, and diagnosis of LD was confirmed by positive urine test for LP antigen. Later, the disease was complicated by acute adult respiratory distress syndrome (ARDS). Treatment with antibiotics (erythromycin, rifampicin, azithromycin) combined with ARDS treatment led to a clinical recovery of the patient together with complete resolution of inflammatory lesions seen on chest radiography. Conclusion. In severe pneumonias it is necessary to consider LD in differential diagnosis, perform tests with aim of detecting LP and apply adequate antibiotic treatment in order to accomplish positive outcome of the therapy and prevent complications.http://www.doiserbia.nb.rs/img/doi/0042-8450/2009/0042-84500912010A.pdfLegionnaires' diseasepenumoniadiagnosis, differentialrespiratory distress syndrome, adulttreatment outcome |
| spellingShingle | Andrijević Ilija Matijašević Jovan Považan Đorđe Kojičić Marija Batranović Uroš Severe form of Legionnaires' disease in an immunocompetent patient Vojnosanitetski Pregled Legionnaires' disease penumonia diagnosis, differential respiratory distress syndrome, adult treatment outcome |
| title | Severe form of Legionnaires' disease in an immunocompetent patient |
| title_full | Severe form of Legionnaires' disease in an immunocompetent patient |
| title_fullStr | Severe form of Legionnaires' disease in an immunocompetent patient |
| title_full_unstemmed | Severe form of Legionnaires' disease in an immunocompetent patient |
| title_short | Severe form of Legionnaires' disease in an immunocompetent patient |
| title_sort | severe form of legionnaires disease in an immunocompetent patient |
| topic | Legionnaires' disease penumonia diagnosis, differential respiratory distress syndrome, adult treatment outcome |
| url | http://www.doiserbia.nb.rs/img/doi/0042-8450/2009/0042-84500912010A.pdf |
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