Chemo-Mechanical Factors That Limit Cellular Force Generation

Chemo-Mechanical Factors That Limit Cellular Force Generation

Cellular traction forces that are dependent on actin-myosin activity are necessary for numerous developmental and physiological processes. As traction force emerges as a promising cancer biomarker there is a growing need to understand force generation in response to chemical and mechanical cues. Our...

Full description

Bibliographic Details
Main Authors: Esteban Vazquez-Hidalgo, Carly M. Farris, Amy C. Rowat, Parag Katira
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Physics
Subjects:
cell mechanobiology
focal adhesions
traction forces
actin-myosin contractility
substrate stiffness
Online Access:https://www.frontiersin.org/articles/10.3389/fphy.2022.831776/full

Similar Items

Similar Items