GLIS3 regulates transcription of thyroid hormone biosynthetic genes in coordination with other thyroid transcription factors

Abstract Background Loss of the transcription factor GLI-Similar 3 (GLIS3) function causes congenital hypothyroidism (CH) in both humans and mice due to decreased expression of several thyroid hormone (TH) biosynthetic genes in thyroid follicular cells. Whether and to what extent, GLIS3 regulates th...

詳細記述

書誌詳細
主要な著者: Hong Soon Kang, Sara A. Grimm, Raja Jothi, Pilar Santisteban, Anton M. Jetten
フォーマット: 論文
言語:English
出版事項: BMC 2023-02-01
シリーズ:Cell & Bioscience
主題:
オンライン・アクセス:https://doi.org/10.1186/s13578-023-00979-8