GLIS3 regulates transcription of thyroid hormone biosynthetic genes in coordination with other thyroid transcription factors

Abstract Background Loss of the transcription factor GLI-Similar 3 (GLIS3) function causes congenital hypothyroidism (CH) in both humans and mice due to decreased expression of several thyroid hormone (TH) biosynthetic genes in thyroid follicular cells. Whether and to what extent, GLIS3 regulates th...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Hong Soon Kang, Sara A. Grimm, Raja Jothi, Pilar Santisteban, Anton M. Jetten
Формат: Өгүүллэг
Хэл сонгох:English
Хэвлэсэн: BMC 2023-02-01
Цуврал:Cell & Bioscience
Нөхцлүүд:
Онлайн хандалт:https://doi.org/10.1186/s13578-023-00979-8