Analysis of the prevalence and influencing factors of hyperuricemia in children and adolescents aged 6–17 years in northeastern Sichuan Province
Objective: To investigate the factors influencing hyperuricemia in children and adolescents and to provide a scientific basis for early prevention and treatment. Methods: A retrospective study (2017–2021) of the prevalence of hyperuricemia in children and adolescents was conducted, and the factors i...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-11-01
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| Series: | Jornal de Pediatria |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S002175572300061X |
| _version_ | 1797655146325344256 |
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| author | Xuemei Guo Ningting Xiao Xueming Jing Zhennan Zhu Heping Zhang |
| author_facet | Xuemei Guo Ningting Xiao Xueming Jing Zhennan Zhu Heping Zhang |
| author_sort | Xuemei Guo |
| collection | DOAJ |
| description | Objective: To investigate the factors influencing hyperuricemia in children and adolescents and to provide a scientific basis for early prevention and treatment. Methods: A retrospective study (2017–2021) of the prevalence of hyperuricemia in children and adolescents was conducted, and the factors influencing hyperuricemia were analyzed by multi-factor logistic regression. Results: The overall prevalence of hyperuricemia in children and adolescents aged 6–17 years in northeast Sichuan Province was 55.12% (8676/15,739), of which 60.68% (5699/9392) in boys and 46.90% (2977/6347) in girls; the prevalence of hyperuricemia from 2017 to 2021 was 52.40% ( 1540/2939), 52.56% (1642/3124), 52.11% (1825/3502), 58.33% (1691/2899), and 60.40% (1978/3275), respectively; the prevalence rates of 6–12 years old were 48.92% (864/1766), 50.46% (769/1524), and 52.73% (685/1299), 56.99% (693/1216), 35.46% (444/1252), 46.33% (524/1131), 60.50% (720/1190), and 66.82% (739/1106), 58.95% (652/1106), and 62.17% (761/1106) for 13–17 years old, respectively, 62.17% (761/1224), 63.19% (855/1353), and 61.70% (970/1572), respectively. Logistic regression showed that the prevalence of male (OR = 1.451, 95% CI 1.034 to 2.035, p = 0.031), age (OR = 1.074, 95% CI 1.024 to 1.126, p = 0.003), overweight/obesity (OR = 1.733, 95% CI 1.204∼2.494, p = 0.003), blood creatinine (OR = 1.018, 95% CI 1.005∼1.031, p = 0.007), triglycerides (OR = 1.450, 95% CI 1.065∼1.972, p = 0.018), blood calcium (OR = 6.792, 95% CI 1.373∼33.594, p = 0.019), and systolic blood pressure (OR = 1.037, 95% CI 1.018∼1.057, p < 0.001) were influential factors for the development of hyperuricemia. Conclusion: The prevalence of hyperuricemia was higher in children and adolescents aged 6–17 years in northeastern Sichuan Province, with a higher prevalence in boys than in girls, and the prevalence increased with age. |
| first_indexed | 2024-03-11T17:09:55Z |
| format | Article |
| id | doaj.art-00dc048be6cf441d866fd04430dcf79a |
| institution | Directory Open Access Journal |
| issn | 0021-7557 |
| language | English |
| last_indexed | 2024-03-11T17:09:55Z |
| publishDate | 2023-11-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Jornal de Pediatria |
| spelling | doaj.art-00dc048be6cf441d866fd04430dcf79a2023-10-20T06:37:57ZengElsevierJornal de Pediatria0021-75572023-11-01996604609Analysis of the prevalence and influencing factors of hyperuricemia in children and adolescents aged 6–17 years in northeastern Sichuan ProvinceXuemei Guo0Ningting Xiao1Xueming Jing2Zhennan Zhu3Heping Zhang4Corresponding author.; Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, ChinaAffiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, ChinaAffiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, ChinaAffiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, ChinaAffiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, ChinaObjective: To investigate the factors influencing hyperuricemia in children and adolescents and to provide a scientific basis for early prevention and treatment. Methods: A retrospective study (2017–2021) of the prevalence of hyperuricemia in children and adolescents was conducted, and the factors influencing hyperuricemia were analyzed by multi-factor logistic regression. Results: The overall prevalence of hyperuricemia in children and adolescents aged 6–17 years in northeast Sichuan Province was 55.12% (8676/15,739), of which 60.68% (5699/9392) in boys and 46.90% (2977/6347) in girls; the prevalence of hyperuricemia from 2017 to 2021 was 52.40% ( 1540/2939), 52.56% (1642/3124), 52.11% (1825/3502), 58.33% (1691/2899), and 60.40% (1978/3275), respectively; the prevalence rates of 6–12 years old were 48.92% (864/1766), 50.46% (769/1524), and 52.73% (685/1299), 56.99% (693/1216), 35.46% (444/1252), 46.33% (524/1131), 60.50% (720/1190), and 66.82% (739/1106), 58.95% (652/1106), and 62.17% (761/1106) for 13–17 years old, respectively, 62.17% (761/1224), 63.19% (855/1353), and 61.70% (970/1572), respectively. Logistic regression showed that the prevalence of male (OR = 1.451, 95% CI 1.034 to 2.035, p = 0.031), age (OR = 1.074, 95% CI 1.024 to 1.126, p = 0.003), overweight/obesity (OR = 1.733, 95% CI 1.204∼2.494, p = 0.003), blood creatinine (OR = 1.018, 95% CI 1.005∼1.031, p = 0.007), triglycerides (OR = 1.450, 95% CI 1.065∼1.972, p = 0.018), blood calcium (OR = 6.792, 95% CI 1.373∼33.594, p = 0.019), and systolic blood pressure (OR = 1.037, 95% CI 1.018∼1.057, p < 0.001) were influential factors for the development of hyperuricemia. Conclusion: The prevalence of hyperuricemia was higher in children and adolescents aged 6–17 years in northeastern Sichuan Province, with a higher prevalence in boys than in girls, and the prevalence increased with age.http://www.sciencedirect.com/science/article/pii/S002175572300061XChildrenAdolescentsHyperuricemiaPrevalenceInfluencing factors |
| spellingShingle | Xuemei Guo Ningting Xiao Xueming Jing Zhennan Zhu Heping Zhang Analysis of the prevalence and influencing factors of hyperuricemia in children and adolescents aged 6–17 years in northeastern Sichuan Province Jornal de Pediatria Children Adolescents Hyperuricemia Prevalence Influencing factors |
| title | Analysis of the prevalence and influencing factors of hyperuricemia in children and adolescents aged 6–17 years in northeastern Sichuan Province |
| title_full | Analysis of the prevalence and influencing factors of hyperuricemia in children and adolescents aged 6–17 years in northeastern Sichuan Province |
| title_fullStr | Analysis of the prevalence and influencing factors of hyperuricemia in children and adolescents aged 6–17 years in northeastern Sichuan Province |
| title_full_unstemmed | Analysis of the prevalence and influencing factors of hyperuricemia in children and adolescents aged 6–17 years in northeastern Sichuan Province |
| title_short | Analysis of the prevalence and influencing factors of hyperuricemia in children and adolescents aged 6–17 years in northeastern Sichuan Province |
| title_sort | analysis of the prevalence and influencing factors of hyperuricemia in children and adolescents aged 6 17 years in northeastern sichuan province |
| topic | Children Adolescents Hyperuricemia Prevalence Influencing factors |
| url | http://www.sciencedirect.com/science/article/pii/S002175572300061X |
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