Evaluation of a collagen-chitosan hydrogel for potential use as a pro-angiogenic site for islet transplantation.

Islet transplantation to treat type 1 diabetes (T1D) has shown varied long-term success, due in part to insufficient blood supply to maintain the islets. In the current study, collagen and collagen:chitosan (10:1) hydrogels, +/- circulating angiogenic cells (CACs), were compared for their ability to...

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Bibliographic Details
Main Authors: Joanne E McBane, Branka Vulesevic, Donna T Padavan, Kimberly A McEwan, Gregory S Korbutt, Erik J Suuronen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3799615?pdf=render