Isl1 promotes gene transcription through physical interaction with Set1/Mll complexes

Isl1 promotes gene transcription through physical interaction with Set1/Mll complexes

Histone H3 lysine 4 (H3K4) methylation is generally recognized as a prominent marker of gene activation. While Set1/Mll complexes are major methyltransferases that are responsible for H3K4 methylation, the mechanism of how these complexes are recruited into the target gene promotor is still unclear....

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Bibliographic Details
Main Authors: Zhe Liu, Weijing Hu, Yali Qin, Li Sun, Lingyun Jing, Manman Lu, Yan Li, Jing Qu, Zhenhua Yang
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:European Journal of Cell Biology
Subjects:
H3K4 methylation
Set1/Mll complexes
Isl1
Gene expression
Online Access:http://www.sciencedirect.com/science/article/pii/S0171933523000109

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