The Nexus of Diet, Gut Microbiota and Inflammatory Bowel Diseases in Dogs
Canine inflammatory bowel diseases (IBD) are of increasing interest in veterinary medicine. They refer to complex and debilitating conditions of dogs’ gastrointestinal tract. Although little evidence for causal inferences is currently available, it is believed that IBD pathophysiology entails intric...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-11-01
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| Series: | Metabolites |
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| Online Access: | https://www.mdpi.com/2218-1989/12/12/1176 |
| _version_ | 1827637790080237568 |
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| author | Soufien Rhimi Aicha Kriaa Vincent Mariaule Amel Saidi Amandine Drut Amin Jablaoui Nizar Akermi Emmanuelle Maguin Juan Hernandez Moez Rhimi |
| author_facet | Soufien Rhimi Aicha Kriaa Vincent Mariaule Amel Saidi Amandine Drut Amin Jablaoui Nizar Akermi Emmanuelle Maguin Juan Hernandez Moez Rhimi |
| author_sort | Soufien Rhimi |
| collection | DOAJ |
| description | Canine inflammatory bowel diseases (IBD) are of increasing interest in veterinary medicine. They refer to complex and debilitating conditions of dogs’ gastrointestinal tract. Although little evidence for causal inferences is currently available, it is believed that IBD pathophysiology entails intricate interactions between environmental factors, the intestinal immune system, and the microbial communities that colonize the gut. To better understand the mechanisms underlying these disorders, leveraging factors associated with the development of these diseases is imperative. Of these factors, emerging evidence supports the role of dietary patterns as key players influencing the composition and function of gut microbes, with subsequent effects on health and disease. In this review, we particularly focus on addressing IBD in dogs and discuss how specific nutrients may elicit or relieve gut inflammation. Gaining mechanistic insights into such interplay and the underpinning mechanisms is key to inferring dietary recommendations, and setting up new and promising therapeutics. |
| first_indexed | 2024-03-09T16:06:43Z |
| format | Article |
| id | doaj.art-00deb0a320fd4698af4e0f0557b03f0a |
| institution | Directory Open Access Journal |
| issn | 2218-1989 |
| language | English |
| last_indexed | 2024-03-09T16:06:43Z |
| publishDate | 2022-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Metabolites |
| spelling | doaj.art-00deb0a320fd4698af4e0f0557b03f0a2023-11-24T16:37:00ZengMDPI AGMetabolites2218-19892022-11-011212117610.3390/metabo12121176The Nexus of Diet, Gut Microbiota and Inflammatory Bowel Diseases in DogsSoufien Rhimi0Aicha Kriaa1Vincent Mariaule2Amel Saidi3Amandine Drut4Amin Jablaoui5Nizar Akermi6Emmanuelle Maguin7Juan Hernandez8Moez Rhimi9Microbiota Interaction with Human and Animal Team (MIHA), Micalis Institute, AgroParisTech, Université Paris-Saclay, Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement, 78350 Jouy-en-Josas, FranceMicrobiota Interaction with Human and Animal Team (MIHA), Micalis Institute, AgroParisTech, Université Paris-Saclay, Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement, 78350 Jouy-en-Josas, FranceMicrobiota Interaction with Human and Animal Team (MIHA), Micalis Institute, AgroParisTech, Université Paris-Saclay, Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement, 78350 Jouy-en-Josas, FranceMicrobiota Interaction with Human and Animal Team (MIHA), Micalis Institute, AgroParisTech, Université Paris-Saclay, Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement, 78350 Jouy-en-Josas, FranceMicrobiota Interaction with Human and Animal Team (MIHA), Micalis Institute, AgroParisTech, Université Paris-Saclay, Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement, 78350 Jouy-en-Josas, FranceMicrobiota Interaction with Human and Animal Team (MIHA), Micalis Institute, AgroParisTech, Université Paris-Saclay, Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement, 78350 Jouy-en-Josas, FranceMicrobiota Interaction with Human and Animal Team (MIHA), Micalis Institute, AgroParisTech, Université Paris-Saclay, Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement, 78350 Jouy-en-Josas, FranceMicrobiota Interaction with Human and Animal Team (MIHA), Micalis Institute, AgroParisTech, Université Paris-Saclay, Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement, 78350 Jouy-en-Josas, FranceMicrobiota Interaction with Human and Animal Team (MIHA), Micalis Institute, AgroParisTech, Université Paris-Saclay, Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement, 78350 Jouy-en-Josas, FranceMicrobiota Interaction with Human and Animal Team (MIHA), Micalis Institute, AgroParisTech, Université Paris-Saclay, Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement, 78350 Jouy-en-Josas, FranceCanine inflammatory bowel diseases (IBD) are of increasing interest in veterinary medicine. They refer to complex and debilitating conditions of dogs’ gastrointestinal tract. Although little evidence for causal inferences is currently available, it is believed that IBD pathophysiology entails intricate interactions between environmental factors, the intestinal immune system, and the microbial communities that colonize the gut. To better understand the mechanisms underlying these disorders, leveraging factors associated with the development of these diseases is imperative. Of these factors, emerging evidence supports the role of dietary patterns as key players influencing the composition and function of gut microbes, with subsequent effects on health and disease. In this review, we particularly focus on addressing IBD in dogs and discuss how specific nutrients may elicit or relieve gut inflammation. Gaining mechanistic insights into such interplay and the underpinning mechanisms is key to inferring dietary recommendations, and setting up new and promising therapeutics.https://www.mdpi.com/2218-1989/12/12/1176canine inflammatory bowel disease (IBD)dietgut microbiotaholobiont |
| spellingShingle | Soufien Rhimi Aicha Kriaa Vincent Mariaule Amel Saidi Amandine Drut Amin Jablaoui Nizar Akermi Emmanuelle Maguin Juan Hernandez Moez Rhimi The Nexus of Diet, Gut Microbiota and Inflammatory Bowel Diseases in Dogs Metabolites canine inflammatory bowel disease (IBD) diet gut microbiota holobiont |
| title | The Nexus of Diet, Gut Microbiota and Inflammatory Bowel Diseases in Dogs |
| title_full | The Nexus of Diet, Gut Microbiota and Inflammatory Bowel Diseases in Dogs |
| title_fullStr | The Nexus of Diet, Gut Microbiota and Inflammatory Bowel Diseases in Dogs |
| title_full_unstemmed | The Nexus of Diet, Gut Microbiota and Inflammatory Bowel Diseases in Dogs |
| title_short | The Nexus of Diet, Gut Microbiota and Inflammatory Bowel Diseases in Dogs |
| title_sort | nexus of diet gut microbiota and inflammatory bowel diseases in dogs |
| topic | canine inflammatory bowel disease (IBD) diet gut microbiota holobiont |
| url | https://www.mdpi.com/2218-1989/12/12/1176 |
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