From Innovation to Implementation: The Evolution of HIV Pre-Exposure Prophylaxis and Future Implications

Pre-exposure prophylaxis (PrEP) is a highly effective HIV-prevention strategy that involves the continuous administration of antiretroviral drugs to HIV-negative individuals with a substantial risk of contracting an HIV infection. The use of PrEP has shown a reduction in the risk of HIV acquisition...

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Main Authors: Marta Rosas Cancio-Suárez, Jorge Díaz-Álvarez, Raquel Ron, Javier Martínez-Sanz, Sergio Serrano-Villar, Santiago Moreno, Matilde Sánchez-Conde
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Pathogens
Subjects:
Online Access:https://www.mdpi.com/2076-0817/12/7/924
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author Marta Rosas Cancio-Suárez
Jorge Díaz-Álvarez
Raquel Ron
Javier Martínez-Sanz
Sergio Serrano-Villar
Santiago Moreno
Matilde Sánchez-Conde
author_facet Marta Rosas Cancio-Suárez
Jorge Díaz-Álvarez
Raquel Ron
Javier Martínez-Sanz
Sergio Serrano-Villar
Santiago Moreno
Matilde Sánchez-Conde
author_sort Marta Rosas Cancio-Suárez
collection DOAJ
description Pre-exposure prophylaxis (PrEP) is a highly effective HIV-prevention strategy that involves the continuous administration of antiretroviral drugs to HIV-negative individuals with a substantial risk of contracting an HIV infection. The use of PrEP has shown a reduction in the risk of HIV acquisition through sexual intercourse by up to 99%. Despite its effectiveness, PrEP uptake remains low among populations at high risk of HIV infection. This highlights the need for further research in strategies to enhance awareness and uptake of PrEP amongst these specific populations. This article presents a comprehensive overview of the existing literature on the effectiveness of PrEP in reducing HIV transmission rates. Additionally, we examine the obstacles related to PrEP implementation and uptake and put forward potential strategies to raise awareness and improve its use among populations at an increased risk of contracting HIV.
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spelling doaj.art-00e10635d7b34b11be16c772aadf3d0b2023-11-18T20:50:58ZengMDPI AGPathogens2076-08172023-07-0112792410.3390/pathogens12070924From Innovation to Implementation: The Evolution of HIV Pre-Exposure Prophylaxis and Future ImplicationsMarta Rosas Cancio-Suárez0Jorge Díaz-Álvarez1Raquel Ron2Javier Martínez-Sanz3Sergio Serrano-Villar4Santiago Moreno5Matilde Sánchez-Conde6Infectious Diseases Department, Hospital Ramón y Cajal, Carretera de Colmenar Km 9.1, 28034 Madrid, SpainInfectious Diseases Department, Hospital Ramón y Cajal, Carretera de Colmenar Km 9.1, 28034 Madrid, SpainInfectious Diseases Department, Hospital Ramón y Cajal, Carretera de Colmenar Km 9.1, 28034 Madrid, SpainInfectious Diseases Department, Hospital Ramón y Cajal, Carretera de Colmenar Km 9.1, 28034 Madrid, SpainInfectious Diseases Department, Hospital Ramón y Cajal, Carretera de Colmenar Km 9.1, 28034 Madrid, SpainInfectious Diseases Department, Hospital Ramón y Cajal, Carretera de Colmenar Km 9.1, 28034 Madrid, SpainInfectious Diseases Department, Hospital Ramón y Cajal, Carretera de Colmenar Km 9.1, 28034 Madrid, SpainPre-exposure prophylaxis (PrEP) is a highly effective HIV-prevention strategy that involves the continuous administration of antiretroviral drugs to HIV-negative individuals with a substantial risk of contracting an HIV infection. The use of PrEP has shown a reduction in the risk of HIV acquisition through sexual intercourse by up to 99%. Despite its effectiveness, PrEP uptake remains low among populations at high risk of HIV infection. This highlights the need for further research in strategies to enhance awareness and uptake of PrEP amongst these specific populations. This article presents a comprehensive overview of the existing literature on the effectiveness of PrEP in reducing HIV transmission rates. Additionally, we examine the obstacles related to PrEP implementation and uptake and put forward potential strategies to raise awareness and improve its use among populations at an increased risk of contracting HIV.https://www.mdpi.com/2076-0817/12/7/924pre-exposure prophylaxisHIVprevention strategies
spellingShingle Marta Rosas Cancio-Suárez
Jorge Díaz-Álvarez
Raquel Ron
Javier Martínez-Sanz
Sergio Serrano-Villar
Santiago Moreno
Matilde Sánchez-Conde
From Innovation to Implementation: The Evolution of HIV Pre-Exposure Prophylaxis and Future Implications
Pathogens
pre-exposure prophylaxis
HIV
prevention strategies
title From Innovation to Implementation: The Evolution of HIV Pre-Exposure Prophylaxis and Future Implications
title_full From Innovation to Implementation: The Evolution of HIV Pre-Exposure Prophylaxis and Future Implications
title_fullStr From Innovation to Implementation: The Evolution of HIV Pre-Exposure Prophylaxis and Future Implications
title_full_unstemmed From Innovation to Implementation: The Evolution of HIV Pre-Exposure Prophylaxis and Future Implications
title_short From Innovation to Implementation: The Evolution of HIV Pre-Exposure Prophylaxis and Future Implications
title_sort from innovation to implementation the evolution of hiv pre exposure prophylaxis and future implications
topic pre-exposure prophylaxis
HIV
prevention strategies
url https://www.mdpi.com/2076-0817/12/7/924
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