Peripheral SLC6A4 DNA methylation is associated with in vivo measures of human brain serotonin synthesis and childhood physical aggression.

Peripheral SLC6A4 DNA methylation is associated with in vivo measures of human brain serotonin synthesis and childhood physical aggression.

The main challenge in addressing the role of DNA methylation in human behaviour is the fact that the brain is inaccessible to epigenetic analysis in living humans. Using positron emission tomography (PET) measures of brain serotonin (5-HT) synthesis, we found in a longitudinal sample that adult male...

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Bibliographic Details
Main Authors:	Dongsha Wang, Moshe Szyf, Chawki Benkelfat, Nadine Provençal, Gustavo Turecki, Doretta Caramaschi, Sylvana M Côté, Frank Vitaro, Richard E Tremblay, Linda Booij
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2012-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC3379993?pdf=render

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