Insulin Biosynthetic Interaction Network Component, TMEM24, Facilitates Insulin Reserve Pool Release
Insulin homeostasis in pancreatic β cells is now recognized as a critical element in the progression of obesity and type II diabetes (T2D). Proteins that interact with insulin to direct its sequential synthesis, folding, trafficking, and packaging into reserve granules in order to manage release in...
Main Authors: | Anita Pottekat, Scott Becker, Kathryn R. Spencer, John R. Yates, III, Gerard Manning, Pamela Itkin-Ansari, William E. Balch |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2013-09-01
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Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124713004129 |
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