Application of intracameral moxifloxacin to prevent endophthalmitis in cataract surgery
AIM: To evaluate the safety and efficacy of intracameral moxifloxacin in preventing endophthalmitis after cataract surgery.<p>METHODS:Sixty-five eyes of 65 patients underwent cataract surgery between January and June 2012. Some patients received intracameral moxifloxacin at the end of surgery,...
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| Format: | Article |
| Language: | English |
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Press of International Journal of Ophthalmology (IJO PRESS)
2015-10-01
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| Series: | Guoji Yanke Zazhi |
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| Online Access: | http://ies.ijo.cn/cn_publish/2015/10/201510002.pdf |
| _version_ | 1811240195143499776 |
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| author | Servet Cetinkaya Yasemin F Cetinkaya Nursen O Acir Zeynep Dadaci |
| author_facet | Servet Cetinkaya Yasemin F Cetinkaya Nursen O Acir Zeynep Dadaci |
| author_sort | Servet Cetinkaya |
| collection | DOAJ |
| description | AIM: To evaluate the safety and efficacy of intracameral moxifloxacin in preventing endophthalmitis after cataract surgery.<p>METHODS:Sixty-five eyes of 65 patients underwent cataract surgery between January and June 2012. Some patients received intracameral moxifloxacin at the end of surgery, while others did not(controls). Pre- and postperative logarithm of the minimum angle of resolution(logMAR)best corrected visual acuity(BCVA), intraocular pressure(IOP), corneal edema, and anterior chamber(AC)status were examined.<p>RESULTS: Thirty-three patients(19 males, 14 females); average age, 64.81±11.61y(range: 41-82y)received moxifloxacin and 32 patients(15 males, 17 females); average age, 65.43±11.10y(range: 42-81y)did not. The differences in patient age(<i>P</i>=0.827)and sex(<i>P</i>=0.396)were insignificant. Preoperative BCVA was approximately 20/130 in both groups. After surgery, moxifloxacin and control patients had a BCVA of 20/25 and 20/23, respectively(<i>P</i>=0.160). Preoperative IOP was 14.93±2.77mmHg(range: 11-21mmHg)in moxifloxacin patients and 15.06±2.42mm Hg(range: 12-21mmHg)in controls(<i>P</i>=0.850). After surgery, IOP was not statistically different between two groups(moxifloxacin: 14.06±2.31(range: 10-19mmHg), controls: 14.03±2.36mmHg(range: 10-19mmHg), <i>P</i>=0.960). Slight differences in corneal edema(<i>P</i>=0.623)and anterior chamber cell(<i>P</i>=0.726)incidences between two groups were not statistically significant. <p>CONCLUSION: Intracameral moxifloxacin is safe and effective in preventing endophtalmitis after cataract surgery. |
| first_indexed | 2024-04-12T13:14:49Z |
| format | Article |
| id | doaj.art-00eb4d1fc0044cfc8b39521f1346f0bf |
| institution | Directory Open Access Journal |
| issn | 1672-5123 1672-5123 |
| language | English |
| last_indexed | 2024-04-12T13:14:49Z |
| publishDate | 2015-10-01 |
| publisher | Press of International Journal of Ophthalmology (IJO PRESS) |
| record_format | Article |
| series | Guoji Yanke Zazhi |
| spelling | doaj.art-00eb4d1fc0044cfc8b39521f1346f0bf2022-12-22T03:31:43ZengPress of International Journal of Ophthalmology (IJO PRESS)Guoji Yanke Zazhi1672-51231672-51232015-10-0115101680168310.3980/j.issn.1672-5123.2015.10.02Application of intracameral moxifloxacin to prevent endophthalmitis in cataract surgeryServet Cetinkaya0Yasemin F Cetinkaya1Nursen O Acir2Zeynep Dadaci3Ophthalmology Clinics, Turkish Red Crescent Hospital, Konya 42200, TurkeyDepartment of Ophthalmology, Ataturk Training and Research Hospital, Ankara 06800, TurkeyDepartment of Ophthalmology, Faculty of Medicine, Mevlana University, Konya 42200, TurkeyDepartment of Ophthalmology, Faculty of Medicine, Mevlana University, Konya 42200, TurkeyAIM: To evaluate the safety and efficacy of intracameral moxifloxacin in preventing endophthalmitis after cataract surgery.<p>METHODS:Sixty-five eyes of 65 patients underwent cataract surgery between January and June 2012. Some patients received intracameral moxifloxacin at the end of surgery, while others did not(controls). Pre- and postperative logarithm of the minimum angle of resolution(logMAR)best corrected visual acuity(BCVA), intraocular pressure(IOP), corneal edema, and anterior chamber(AC)status were examined.<p>RESULTS: Thirty-three patients(19 males, 14 females); average age, 64.81±11.61y(range: 41-82y)received moxifloxacin and 32 patients(15 males, 17 females); average age, 65.43±11.10y(range: 42-81y)did not. The differences in patient age(<i>P</i>=0.827)and sex(<i>P</i>=0.396)were insignificant. Preoperative BCVA was approximately 20/130 in both groups. After surgery, moxifloxacin and control patients had a BCVA of 20/25 and 20/23, respectively(<i>P</i>=0.160). Preoperative IOP was 14.93±2.77mmHg(range: 11-21mmHg)in moxifloxacin patients and 15.06±2.42mm Hg(range: 12-21mmHg)in controls(<i>P</i>=0.850). After surgery, IOP was not statistically different between two groups(moxifloxacin: 14.06±2.31(range: 10-19mmHg), controls: 14.03±2.36mmHg(range: 10-19mmHg), <i>P</i>=0.960). Slight differences in corneal edema(<i>P</i>=0.623)and anterior chamber cell(<i>P</i>=0.726)incidences between two groups were not statistically significant. <p>CONCLUSION: Intracameral moxifloxacin is safe and effective in preventing endophtalmitis after cataract surgery.http://ies.ijo.cn/cn_publish/2015/10/201510002.pdfphacoemulsificationendophthalmitisprophylaxismoxifloxacin |
| spellingShingle | Servet Cetinkaya Yasemin F Cetinkaya Nursen O Acir Zeynep Dadaci Application of intracameral moxifloxacin to prevent endophthalmitis in cataract surgery Guoji Yanke Zazhi phacoemulsification endophthalmitis prophylaxis moxifloxacin |
| title | Application of intracameral moxifloxacin to prevent endophthalmitis in cataract surgery |
| title_full | Application of intracameral moxifloxacin to prevent endophthalmitis in cataract surgery |
| title_fullStr | Application of intracameral moxifloxacin to prevent endophthalmitis in cataract surgery |
| title_full_unstemmed | Application of intracameral moxifloxacin to prevent endophthalmitis in cataract surgery |
| title_short | Application of intracameral moxifloxacin to prevent endophthalmitis in cataract surgery |
| title_sort | application of intracameral moxifloxacin to prevent endophthalmitis in cataract surgery |
| topic | phacoemulsification endophthalmitis prophylaxis moxifloxacin |
| url | http://ies.ijo.cn/cn_publish/2015/10/201510002.pdf |
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