The dual role of autophagy in periprosthetic osteolysis

The dual role of autophagy in periprosthetic osteolysis

Periprosthetic osteolysis (PPO) induced by wear particles is an important cause of aseptic loosening after artificial joint replacement, among which the imbalance of osteogenesis and osteoclastic processes occupies a central position. The cells involved in PPO mainly include osteoclasts (macrophages...

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Bibliographic Details
Main Authors:	Zhaoyang Yin, Ge Gong, Xiang Wang, Wei Liu, Bin Wang, Jian Yin
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-03-01
Series:	Frontiers in Cell and Developmental Biology
Subjects:	periprosthetic osteolysis autophagy mitophagy aseptic loosening RANKL
Online Access:	https://www.frontiersin.org/articles/10.3389/fcell.2023.1123753/full

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