Comparison of the effects of 3 different anti-VEGF drugs on cornea thickness, lens thickness and anterior chamber depth

To compare the long-term effects of 3 different anti-VEGF molecules on the lens, cornea and anterior chamber in phakic patients who have received consecutive intravitreal injections. 157 patients who did not have corneal pathology but were treated with 1.25mg/0.05ml intravitreal bevacizumab, 0.5mg/0...

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Main Authors: Mehmet Tahir Eski, Kuddusi Teberik, Taha Sezer
Format: Article
Language:English
Published: Society of Turaz Bilim 2023-03-01
Series:Medicine Science
Subjects:
Online Access:https://www.medicinescience.org/?mno=135972
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author Mehmet Tahir Eski
Kuddusi Teberik
Taha Sezer
author_facet Mehmet Tahir Eski
Kuddusi Teberik
Taha Sezer
author_sort Mehmet Tahir Eski
collection DOAJ
description To compare the long-term effects of 3 different anti-VEGF molecules on the lens, cornea and anterior chamber in phakic patients who have received consecutive intravitreal injections. 157 patients who did not have corneal pathology but were treated with 1.25mg/0.05ml intravitreal bevacizumab, 0.5mg/0.5ml ranibizumab or 2mg/0.05ml aflibercept injections due to diabetic macular edema were retrospectively analyzed in our clinic. Patients who received three consecutive monthly injections were included to the study. Corneal thickness, lens thickness and anterior chamber depth measurements which were taken before the injections, 1 month after the first injection, 1 month after the second injection, and 1 month after the third injection were used in the study. There was no statistical difference between the bevacizumab, ranibizumab, aflibercept and control group in terms of preoperative specifications such as number of patients, gender and age average. A statistically significant difference was found between the 4 anterior chamber depth measurements in the control group, Ranibizumab drug group, and Bevacizumab and Aflibercept drug groups (p [Med-Science 2023; 12(1.000): 76-80]
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spelling doaj.art-00efcaf87b314e2e9ef263586211a3042024-02-12T10:34:07ZengSociety of Turaz BilimMedicine Science2147-06342023-03-01121768010.5455/medscience.2023.01.02135972Comparison of the effects of 3 different anti-VEGF drugs on cornea thickness, lens thickness and anterior chamber depthMehmet Tahir Eski0Kuddusi Teberik1Taha Sezer2Ergenekon mahalle 104. Sokak Private Neon Hospital Erzincan Merkez Orhangazi Mah., Konuralp 500. Cd, No: 125/7, 81450, Duzce, Turkey Orhangazi Mah., Konuralp 500. Cd, No: 125/7, 81450, Duzce, TurkeyTo compare the long-term effects of 3 different anti-VEGF molecules on the lens, cornea and anterior chamber in phakic patients who have received consecutive intravitreal injections. 157 patients who did not have corneal pathology but were treated with 1.25mg/0.05ml intravitreal bevacizumab, 0.5mg/0.5ml ranibizumab or 2mg/0.05ml aflibercept injections due to diabetic macular edema were retrospectively analyzed in our clinic. Patients who received three consecutive monthly injections were included to the study. Corneal thickness, lens thickness and anterior chamber depth measurements which were taken before the injections, 1 month after the first injection, 1 month after the second injection, and 1 month after the third injection were used in the study. There was no statistical difference between the bevacizumab, ranibizumab, aflibercept and control group in terms of preoperative specifications such as number of patients, gender and age average. A statistically significant difference was found between the 4 anterior chamber depth measurements in the control group, Ranibizumab drug group, and Bevacizumab and Aflibercept drug groups (p [Med-Science 2023; 12(1.000): 76-80]https://www.medicinescience.org/?mno=135972bevacizumabafliberceptranibizumabanterior chamber
spellingShingle Mehmet Tahir Eski
Kuddusi Teberik
Taha Sezer
Comparison of the effects of 3 different anti-VEGF drugs on cornea thickness, lens thickness and anterior chamber depth
Medicine Science
bevacizumab
aflibercept
ranibizumab
anterior chamber
title Comparison of the effects of 3 different anti-VEGF drugs on cornea thickness, lens thickness and anterior chamber depth
title_full Comparison of the effects of 3 different anti-VEGF drugs on cornea thickness, lens thickness and anterior chamber depth
title_fullStr Comparison of the effects of 3 different anti-VEGF drugs on cornea thickness, lens thickness and anterior chamber depth
title_full_unstemmed Comparison of the effects of 3 different anti-VEGF drugs on cornea thickness, lens thickness and anterior chamber depth
title_short Comparison of the effects of 3 different anti-VEGF drugs on cornea thickness, lens thickness and anterior chamber depth
title_sort comparison of the effects of 3 different anti vegf drugs on cornea thickness lens thickness and anterior chamber depth
topic bevacizumab
aflibercept
ranibizumab
anterior chamber
url https://www.medicinescience.org/?mno=135972
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AT kuddusiteberik comparisonoftheeffectsof3differentantivegfdrugsoncorneathicknesslensthicknessandanteriorchamberdepth
AT tahasezer comparisonoftheeffectsof3differentantivegfdrugsoncorneathicknesslensthicknessandanteriorchamberdepth