Multiple sclerosis and personality traits: associations with depression and anxiety
Abstract Background Depression and anxiety are commonly observed in people with multiple sclerosis (pwMS). There is a growing body of literature supporting the hypothesis that personality traits can influence the mood disorders. This study aimed to investigate the personality traits and their relati...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2024-03-01
|
| Series: | European Journal of Medical Research |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s40001-024-01772-0 |
| _version_ | 1797259401754574848 |
|---|---|
| author | Saeed Vaheb Yousef Mokary Mohammad Yazdan Panah Aysa Shaygannejad Alireza Afshari-Safavi Majid Ghasemi Vahid Shaygannejad Elham Moases Ghaffary Omid Mirmosayyeb |
| author_facet | Saeed Vaheb Yousef Mokary Mohammad Yazdan Panah Aysa Shaygannejad Alireza Afshari-Safavi Majid Ghasemi Vahid Shaygannejad Elham Moases Ghaffary Omid Mirmosayyeb |
| author_sort | Saeed Vaheb |
| collection | DOAJ |
| description | Abstract Background Depression and anxiety are commonly observed in people with multiple sclerosis (pwMS). There is a growing body of literature supporting the hypothesis that personality traits can influence the mood disorders. This study aimed to investigate the personality traits and their relationships with depression and anxiety among pwMS. Methods 234 pwMS were involved in this cross-sectional study. Personality traits, depression, and anxiety were assessed using the NEO Five-Factor Inventory (NEO-FFI) and Hospital Anxiety and Depression Scale (HADS), respectively. Pearson's correlation coefficient and generalized linear model were employed to evaluate the relationships between demographic and clinical characteristics, NEO-FFI, and HADS subscales. Results In pwMS, longer disease duration was significantly associated with lower level of conscientiousness (β = − 0.23, p = 0.008) and agreeableness (β = − 0.2, p = 0.01). Moreover, higher expanded disability status scale (EDSS) of pwMS had a significant relationship with higher level of neuroticism (β = 0.89, p = 0.01). Increased level of neuroticism was significantly correlated with lower level of extraversion (r = − 0.28, p < 0.001), openness (r = − 0.37, p < 0.001), agreeableness (r = − 0.31, p < 0.001), and conscientiousness (r = − 0.45, p < 0.001). PwMS with higher level of conscientiousness showed more extraversion (r = 0.23, p < 0.001), openness (r = 0.61, p < 0.001), and agreeableness (r = 0.41, p < 0.001). Elevated level of neuroticism was significantly associated with higher level of anxiety (β = 0.47, p < 0.001) and depression (β = 0.11, p < 0.001) among pwMS. Conclusion The co-occurrence of depression and anxiety is probably associated with neuroticism among pwMS. Additionally, the impact of personality traits extends to influencing key disease aspects such as physical disability and disease duration in MS. |
| first_indexed | 2024-04-24T23:08:51Z |
| format | Article |
| id | doaj.art-00f1a2bfeced48bc9f27a2d4f911e0b1 |
| institution | Directory Open Access Journal |
| issn | 2047-783X |
| language | English |
| last_indexed | 2024-04-24T23:08:51Z |
| publishDate | 2024-03-01 |
| publisher | BMC |
| record_format | Article |
| series | European Journal of Medical Research |
| spelling | doaj.art-00f1a2bfeced48bc9f27a2d4f911e0b12024-03-17T12:19:34ZengBMCEuropean Journal of Medical Research2047-783X2024-03-012911810.1186/s40001-024-01772-0Multiple sclerosis and personality traits: associations with depression and anxietySaeed Vaheb0Yousef Mokary1Mohammad Yazdan Panah2Aysa Shaygannejad3Alireza Afshari-Safavi4Majid Ghasemi5Vahid Shaygannejad6Elham Moases Ghaffary7Omid Mirmosayyeb8Isfahan Neurosciences Research Center, Isfahan University of Medical SciencesStudents Research Committee, Shahrekord University of Medical SciencesStudents Research Committee, Shahrekord University of Medical SciencesIsfahan Neurosciences Research Center, Isfahan University of Medical SciencesDepartment of Biostatistics and Epidemiology, Faculty of Health, North Khorasan University of Medical SciencesIsfahan Neurosciences Research Center, Isfahan University of Medical SciencesIsfahan Neurosciences Research Center, Isfahan University of Medical SciencesIsfahan Neurosciences Research Center, Isfahan University of Medical SciencesIsfahan Neurosciences Research Center, Isfahan University of Medical SciencesAbstract Background Depression and anxiety are commonly observed in people with multiple sclerosis (pwMS). There is a growing body of literature supporting the hypothesis that personality traits can influence the mood disorders. This study aimed to investigate the personality traits and their relationships with depression and anxiety among pwMS. Methods 234 pwMS were involved in this cross-sectional study. Personality traits, depression, and anxiety were assessed using the NEO Five-Factor Inventory (NEO-FFI) and Hospital Anxiety and Depression Scale (HADS), respectively. Pearson's correlation coefficient and generalized linear model were employed to evaluate the relationships between demographic and clinical characteristics, NEO-FFI, and HADS subscales. Results In pwMS, longer disease duration was significantly associated with lower level of conscientiousness (β = − 0.23, p = 0.008) and agreeableness (β = − 0.2, p = 0.01). Moreover, higher expanded disability status scale (EDSS) of pwMS had a significant relationship with higher level of neuroticism (β = 0.89, p = 0.01). Increased level of neuroticism was significantly correlated with lower level of extraversion (r = − 0.28, p < 0.001), openness (r = − 0.37, p < 0.001), agreeableness (r = − 0.31, p < 0.001), and conscientiousness (r = − 0.45, p < 0.001). PwMS with higher level of conscientiousness showed more extraversion (r = 0.23, p < 0.001), openness (r = 0.61, p < 0.001), and agreeableness (r = 0.41, p < 0.001). Elevated level of neuroticism was significantly associated with higher level of anxiety (β = 0.47, p < 0.001) and depression (β = 0.11, p < 0.001) among pwMS. Conclusion The co-occurrence of depression and anxiety is probably associated with neuroticism among pwMS. Additionally, the impact of personality traits extends to influencing key disease aspects such as physical disability and disease duration in MS.https://doi.org/10.1186/s40001-024-01772-0Personality traitsDepressionAnxietyMultiple Sclerosis |
| spellingShingle | Saeed Vaheb Yousef Mokary Mohammad Yazdan Panah Aysa Shaygannejad Alireza Afshari-Safavi Majid Ghasemi Vahid Shaygannejad Elham Moases Ghaffary Omid Mirmosayyeb Multiple sclerosis and personality traits: associations with depression and anxiety European Journal of Medical Research Personality traits Depression Anxiety Multiple Sclerosis |
| title | Multiple sclerosis and personality traits: associations with depression and anxiety |
| title_full | Multiple sclerosis and personality traits: associations with depression and anxiety |
| title_fullStr | Multiple sclerosis and personality traits: associations with depression and anxiety |
| title_full_unstemmed | Multiple sclerosis and personality traits: associations with depression and anxiety |
| title_short | Multiple sclerosis and personality traits: associations with depression and anxiety |
| title_sort | multiple sclerosis and personality traits associations with depression and anxiety |
| topic | Personality traits Depression Anxiety Multiple Sclerosis |
| url | https://doi.org/10.1186/s40001-024-01772-0 |
| work_keys_str_mv | AT saeedvaheb multiplesclerosisandpersonalitytraitsassociationswithdepressionandanxiety AT yousefmokary multiplesclerosisandpersonalitytraitsassociationswithdepressionandanxiety AT mohammadyazdanpanah multiplesclerosisandpersonalitytraitsassociationswithdepressionandanxiety AT aysashaygannejad multiplesclerosisandpersonalitytraitsassociationswithdepressionandanxiety AT alirezaafsharisafavi multiplesclerosisandpersonalitytraitsassociationswithdepressionandanxiety AT majidghasemi multiplesclerosisandpersonalitytraitsassociationswithdepressionandanxiety AT vahidshaygannejad multiplesclerosisandpersonalitytraitsassociationswithdepressionandanxiety AT elhammoasesghaffary multiplesclerosisandpersonalitytraitsassociationswithdepressionandanxiety AT omidmirmosayyeb multiplesclerosisandpersonalitytraitsassociationswithdepressionandanxiety |