Improving Respiratory Infection Diagnosis with Deep Learning and Combinatorial Fusion: A Two-Stage Approach Using Chest X-ray Imaging

The challenges of respiratory infections persist as a global health crisis, placing substantial stress on healthcare infrastructures and necessitating ongoing investigation into efficacious treatment modalities. The persistent challenge of respiratory infections, including COVID-19, underscores the...

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Main Authors: Cheng-Tang Pan, Rahul Kumar, Zhi-Hong Wen, Chih-Hsuan Wang, Chun-Yung Chang, Yow-Ling Shiue
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Diagnostics
Subjects:
Online Access:https://www.mdpi.com/2075-4418/14/5/500
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author Cheng-Tang Pan
Rahul Kumar
Zhi-Hong Wen
Chih-Hsuan Wang
Chun-Yung Chang
Yow-Ling Shiue
author_facet Cheng-Tang Pan
Rahul Kumar
Zhi-Hong Wen
Chih-Hsuan Wang
Chun-Yung Chang
Yow-Ling Shiue
author_sort Cheng-Tang Pan
collection DOAJ
description The challenges of respiratory infections persist as a global health crisis, placing substantial stress on healthcare infrastructures and necessitating ongoing investigation into efficacious treatment modalities. The persistent challenge of respiratory infections, including COVID-19, underscores the critical need for enhanced diagnostic methodologies to support early treatment interventions. This study introduces an innovative two-stage data analytics framework that leverages deep learning algorithms through a strategic combinatorial fusion technique, aimed at refining the accuracy of early-stage diagnosis of such infections. Utilizing a comprehensive dataset compiled from publicly available lung X-ray images, the research employs advanced pre-trained deep learning models to navigate the complexities of disease classification, addressing inherent data imbalances through methodical validation processes. The core contribution of this work lies in its novel application of combinatorial fusion, integrating select models to significantly elevate diagnostic precision. This approach not only showcases the adaptability and strength of deep learning in navigating the intricacies of medical imaging but also marks a significant step forward in the utilization of artificial intelligence to improve outcomes in healthcare diagnostics. The study’s findings illuminate the path toward leveraging technological advancements in enhancing diagnostic accuracies, ultimately contributing to the timely and effective treatment of respiratory diseases.
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spelling doaj.art-00f45db714b1478585bb5d42302656de2024-03-12T16:41:58ZengMDPI AGDiagnostics2075-44182024-02-0114550010.3390/diagnostics14050500Improving Respiratory Infection Diagnosis with Deep Learning and Combinatorial Fusion: A Two-Stage Approach Using Chest X-ray ImagingCheng-Tang Pan0Rahul Kumar1Zhi-Hong Wen2Chih-Hsuan Wang3Chun-Yung Chang4Yow-Ling Shiue5Department of Mechanical and Electro-Mechanical Engineering, National Sun Yat-sen University, Kaohsiung 804, TaiwanDepartment of Mechanical and Electro-Mechanical Engineering, National Sun Yat-sen University, Kaohsiung 804, TaiwanDepartment of Marine Biotechnology and Research, National Sun Yat-sen University, Kaohsiung 804, TaiwanDivision of Nephrology and Metabolism, Department of Internal Medicine, Kaohsiung Armed Forces General Hospital, Kaohsiung 804, TaiwanDivision of Nephrology and Metabolism, Department of Internal Medicine, Kaohsiung Armed Forces General Hospital, Kaohsiung 804, TaiwanInstitute of Precision Medicine, National Sun Yat-sen University, Kaohsiung 804, TaiwanThe challenges of respiratory infections persist as a global health crisis, placing substantial stress on healthcare infrastructures and necessitating ongoing investigation into efficacious treatment modalities. The persistent challenge of respiratory infections, including COVID-19, underscores the critical need for enhanced diagnostic methodologies to support early treatment interventions. This study introduces an innovative two-stage data analytics framework that leverages deep learning algorithms through a strategic combinatorial fusion technique, aimed at refining the accuracy of early-stage diagnosis of such infections. Utilizing a comprehensive dataset compiled from publicly available lung X-ray images, the research employs advanced pre-trained deep learning models to navigate the complexities of disease classification, addressing inherent data imbalances through methodical validation processes. The core contribution of this work lies in its novel application of combinatorial fusion, integrating select models to significantly elevate diagnostic precision. This approach not only showcases the adaptability and strength of deep learning in navigating the intricacies of medical imaging but also marks a significant step forward in the utilization of artificial intelligence to improve outcomes in healthcare diagnostics. The study’s findings illuminate the path toward leveraging technological advancements in enhancing diagnostic accuracies, ultimately contributing to the timely and effective treatment of respiratory diseases.https://www.mdpi.com/2075-4418/14/5/500respiratory infectionsdeep learningconvolutional neural network (CNN)lung X-ray imagescombinatorial fusion
spellingShingle Cheng-Tang Pan
Rahul Kumar
Zhi-Hong Wen
Chih-Hsuan Wang
Chun-Yung Chang
Yow-Ling Shiue
Improving Respiratory Infection Diagnosis with Deep Learning and Combinatorial Fusion: A Two-Stage Approach Using Chest X-ray Imaging
Diagnostics
respiratory infections
deep learning
convolutional neural network (CNN)
lung X-ray images
combinatorial fusion
title Improving Respiratory Infection Diagnosis with Deep Learning and Combinatorial Fusion: A Two-Stage Approach Using Chest X-ray Imaging
title_full Improving Respiratory Infection Diagnosis with Deep Learning and Combinatorial Fusion: A Two-Stage Approach Using Chest X-ray Imaging
title_fullStr Improving Respiratory Infection Diagnosis with Deep Learning and Combinatorial Fusion: A Two-Stage Approach Using Chest X-ray Imaging
title_full_unstemmed Improving Respiratory Infection Diagnosis with Deep Learning and Combinatorial Fusion: A Two-Stage Approach Using Chest X-ray Imaging
title_short Improving Respiratory Infection Diagnosis with Deep Learning and Combinatorial Fusion: A Two-Stage Approach Using Chest X-ray Imaging
title_sort improving respiratory infection diagnosis with deep learning and combinatorial fusion a two stage approach using chest x ray imaging
topic respiratory infections
deep learning
convolutional neural network (CNN)
lung X-ray images
combinatorial fusion
url https://www.mdpi.com/2075-4418/14/5/500
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