A review on characteristics and analytical methods of atovaquone – a potent antimalarial agent
Drugs used in the treatment of malaria that is caused by various plasmosium species i.e. P. falciparum, P. vivax are most irresistible disease throughout the world. The different medications are utilized in the treatment of malaria incorporated the Aryl aminoalcohol mixes: Quinine, Quinidine, Chloro...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Creative Pharma Assent
2020-08-01
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| Series: | Journal of Applied Pharmaceutical Research |
| Subjects: | |
| Online Access: | https://japtronline.com/index.php/joapr/article/view/140 |
| _version_ | 1818576731065286656 |
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| author | Sanyam Sharma Rahul Sharma Arti Devi Shammy Jindal Kamya Goyal |
| author_facet | Sanyam Sharma Rahul Sharma Arti Devi Shammy Jindal Kamya Goyal |
| author_sort | Sanyam Sharma |
| collection | DOAJ |
| description | Drugs used in the treatment of malaria that is caused by various plasmosium species i.e. P. falciparum, P. vivax are most irresistible disease throughout the world. The different medications are utilized in the treatment of malaria incorporated the Aryl aminoalcohol mixes: Quinine, Quinidine, Chloroquine, Mefloquine; Antifolate compound: Pyrimethamine, Proguanil, Chlorproguanil, Trimethoprim and Atovaquone. Atovaquone is most effective drug utilized in the treatment of malaria. It must be given in single or in mixture with different antimalarials. An enormous number of methodologies including High Performance Liquid chromatography (HPLC), UV–Visible spectroscopy and Liquid Chromatography-Mass Spectroscopy (LC-MS) are utilized for the determination of atovaquone. Various analytical methods are used for the analysis of pharmaceutical products and these methods were validated according to ICH guidelines (Q1A R2). Thus, this technique can be safely used for the standard quality control analysis of atovaquone. |
| first_indexed | 2024-12-16T06:18:40Z |
| format | Article |
| id | doaj.art-00faad5aaae444d7ade96ec8fbb2d46e |
| institution | Directory Open Access Journal |
| issn | 2348-0335 |
| language | English |
| last_indexed | 2024-12-16T06:18:40Z |
| publishDate | 2020-08-01 |
| publisher | Creative Pharma Assent |
| record_format | Article |
| series | Journal of Applied Pharmaceutical Research |
| spelling | doaj.art-00faad5aaae444d7ade96ec8fbb2d46e2022-12-21T22:41:12ZengCreative Pharma AssentJournal of Applied Pharmaceutical Research2348-03352020-08-0183313710.18231/j.joapr.2020.v.8.i.3.31.37140A review on characteristics and analytical methods of atovaquone – a potent antimalarial agentSanyam Sharma0Rahul Sharma1Arti Devi2Shammy Jindal3Kamya Goyal4Laureate Institute of Pharmacy, Kathog, Jawalamukhi, HP, IndiaLaureate Institute of Pharmacy, V.P.O. Kathog, Teh. Jawalamukhi, Distt. Kangra-176031, Himachal PradeshLaureate Institute of Pharmacy, V.P.O. Kathog, Teh. Jawalamukhi, Distt. Kangra-176031, Himachal PradeshLaureate Institute of Pharmacy, V.P.O. Kathog, Teh. Jawalamukhi, Distt. Kangra-176031, Himachal PradeshLaureate Institute of Pharmacy, Kathog, Jawalamukhi, HPDrugs used in the treatment of malaria that is caused by various plasmosium species i.e. P. falciparum, P. vivax are most irresistible disease throughout the world. The different medications are utilized in the treatment of malaria incorporated the Aryl aminoalcohol mixes: Quinine, Quinidine, Chloroquine, Mefloquine; Antifolate compound: Pyrimethamine, Proguanil, Chlorproguanil, Trimethoprim and Atovaquone. Atovaquone is most effective drug utilized in the treatment of malaria. It must be given in single or in mixture with different antimalarials. An enormous number of methodologies including High Performance Liquid chromatography (HPLC), UV–Visible spectroscopy and Liquid Chromatography-Mass Spectroscopy (LC-MS) are utilized for the determination of atovaquone. Various analytical methods are used for the analysis of pharmaceutical products and these methods were validated according to ICH guidelines (Q1A R2). Thus, this technique can be safely used for the standard quality control analysis of atovaquone.https://japtronline.com/index.php/joapr/article/view/140malaria, antimalarial drugs, atovaquone, analytical methods, hplc |
| spellingShingle | Sanyam Sharma Rahul Sharma Arti Devi Shammy Jindal Kamya Goyal A review on characteristics and analytical methods of atovaquone – a potent antimalarial agent Journal of Applied Pharmaceutical Research malaria, antimalarial drugs, atovaquone, analytical methods, hplc |
| title | A review on characteristics and analytical methods of atovaquone – a potent antimalarial agent |
| title_full | A review on characteristics and analytical methods of atovaquone – a potent antimalarial agent |
| title_fullStr | A review on characteristics and analytical methods of atovaquone – a potent antimalarial agent |
| title_full_unstemmed | A review on characteristics and analytical methods of atovaquone – a potent antimalarial agent |
| title_short | A review on characteristics and analytical methods of atovaquone – a potent antimalarial agent |
| title_sort | review on characteristics and analytical methods of atovaquone a potent antimalarial agent |
| topic | malaria, antimalarial drugs, atovaquone, analytical methods, hplc |
| url | https://japtronline.com/index.php/joapr/article/view/140 |
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