miR‐367 as a therapeutic target in stem‐like cells from embryonal central nervous system tumors

miR‐367 as a therapeutic target in stem‐like cells from embryonal central nervous system tumors

Aberrant expression of the pluripotency factor OCT4A in embryonal tumors of the central nervous system (CNS) is a key factor that contributes to tumor aggressiveness and correlates with poor patient survival. OCT4A overexpression has been shown to up‐regulate miR‐367, a microRNA (miRNA) that regulat...

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Bibliographic Details
Main Authors: Carolini Kaid, Dione Jordan, Heloisa Maria de Siqueira Bueno, Bruno Henrique Silva Araujo, Amanda Assoni, Oswaldo Keith Okamoto
Format: Article
Language:English
Published: Wiley 2019-12-01
Series:Molecular Oncology
Subjects:
cancer stem cell
embryonal CNS tumor
miR‐367
OCT4A
oncogenic biomarker
Online Access:https://doi.org/10.1002/1878-0261.12562

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