Efficacy of topical latanoprost versus minoxidil and betamethasone valerate on the treatment of alopecia areata
Background: Alopecia areata (AA) is one of the most common causes of localized hair loss. There is no universally proven therapy that induces and sustains remission of hair growth in AA. Objective: To compare the efficacy and safety of topical latanoprost, minoxidil and betamethasone valerate on hai...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2018-01-01
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| Series: | Journal of Dermatological Treatment |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/09546634.2017.1330527 |
| _version_ | 1797683716050386944 |
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| author | Amal Ahmad El-Ashmawy Iman Hamed El-Maadawy Gamal Mohamed El-Maghraby |
| author_facet | Amal Ahmad El-Ashmawy Iman Hamed El-Maadawy Gamal Mohamed El-Maghraby |
| author_sort | Amal Ahmad El-Ashmawy |
| collection | DOAJ |
| description | Background: Alopecia areata (AA) is one of the most common causes of localized hair loss. There is no universally proven therapy that induces and sustains remission of hair growth in AA. Objective: To compare the efficacy and safety of topical latanoprost, minoxidil and betamethasone valerate on hair growth in patients with AA. Patients and methods: Hundred patients with AA classified into five groups of 20 treated with: Group I, latanoprost 0.1% lotion; Group II, minoxidil 5% lotion; Group III, betamethasone valerate 0.1% solution; Group IV, combination of latanoprost lotion and betamethasone valerate solution and Group V, a vehicle lotion control group. Results: There was a statistically significant improvement in all therapeutic groups when compared with control group and reduction of severity of alopecia tool score of scalp and beard before and after treatment for all therapeutic groups. Conclusion: Latanoprost, minoxidil and betamethasone valerate are effective and safe in the treatment of patchy AA. The use of latanoprost added to the therapeutic efficacy of topical betamethasone valerate in the treatment of AA and could be an effective adjunctive topical therapy for AA. |
| first_indexed | 2024-03-12T00:19:49Z |
| format | Article |
| id | doaj.art-00fddd4a20bb49f1af8cd5d4cdc62488 |
| institution | Directory Open Access Journal |
| issn | 0954-6634 1471-1753 |
| language | English |
| last_indexed | 2024-03-12T00:19:49Z |
| publishDate | 2018-01-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Journal of Dermatological Treatment |
| spelling | doaj.art-00fddd4a20bb49f1af8cd5d4cdc624882023-09-15T14:08:30ZengTaylor & Francis GroupJournal of Dermatological Treatment0954-66341471-17532018-01-01291556410.1080/09546634.2017.13305271330527Efficacy of topical latanoprost versus minoxidil and betamethasone valerate on the treatment of alopecia areataAmal Ahmad El-Ashmawy0Iman Hamed El-Maadawy1Gamal Mohamed El-Maghraby2Tanta UniversityTanta UniversityTanta UniversityBackground: Alopecia areata (AA) is one of the most common causes of localized hair loss. There is no universally proven therapy that induces and sustains remission of hair growth in AA. Objective: To compare the efficacy and safety of topical latanoprost, minoxidil and betamethasone valerate on hair growth in patients with AA. Patients and methods: Hundred patients with AA classified into five groups of 20 treated with: Group I, latanoprost 0.1% lotion; Group II, minoxidil 5% lotion; Group III, betamethasone valerate 0.1% solution; Group IV, combination of latanoprost lotion and betamethasone valerate solution and Group V, a vehicle lotion control group. Results: There was a statistically significant improvement in all therapeutic groups when compared with control group and reduction of severity of alopecia tool score of scalp and beard before and after treatment for all therapeutic groups. Conclusion: Latanoprost, minoxidil and betamethasone valerate are effective and safe in the treatment of patchy AA. The use of latanoprost added to the therapeutic efficacy of topical betamethasone valerate in the treatment of AA and could be an effective adjunctive topical therapy for AA.http://dx.doi.org/10.1080/09546634.2017.1330527alopecia areatalatanoprostminoxidilbetamethasone valerate |
| spellingShingle | Amal Ahmad El-Ashmawy Iman Hamed El-Maadawy Gamal Mohamed El-Maghraby Efficacy of topical latanoprost versus minoxidil and betamethasone valerate on the treatment of alopecia areata Journal of Dermatological Treatment alopecia areata latanoprost minoxidil betamethasone valerate |
| title | Efficacy of topical latanoprost versus minoxidil and betamethasone valerate on the treatment of alopecia areata |
| title_full | Efficacy of topical latanoprost versus minoxidil and betamethasone valerate on the treatment of alopecia areata |
| title_fullStr | Efficacy of topical latanoprost versus minoxidil and betamethasone valerate on the treatment of alopecia areata |
| title_full_unstemmed | Efficacy of topical latanoprost versus minoxidil and betamethasone valerate on the treatment of alopecia areata |
| title_short | Efficacy of topical latanoprost versus minoxidil and betamethasone valerate on the treatment of alopecia areata |
| title_sort | efficacy of topical latanoprost versus minoxidil and betamethasone valerate on the treatment of alopecia areata |
| topic | alopecia areata latanoprost minoxidil betamethasone valerate |
| url | http://dx.doi.org/10.1080/09546634.2017.1330527 |
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