PD-L1/PD-1 Axis in Multiple Myeloma Microenvironment and a Possible Link with CD38-Mediated Immune-Suppression

PD-L1/PD-1 Axis in Multiple Myeloma Microenvironment and a Possible Link with CD38-Mediated Immune-Suppression

The emerging role of the PD-1/PD-L1 axis in MM immune-microenvironment has been highlighted by several studies. However, discordant data have been reported on PD-1/PD-L1 distribution within the bone marrow (BM) microenvironment of patients with monoclonal gammopathies. In addition, the efficacy of P...

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Bibliographic Details
Main Authors: Federica Costa, Valentina Marchica, Paola Storti, Fabio Malavasi, Nicola Giuliani
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Cancers
Subjects:
PD-L1
PD-1
multiple myeloma
microenvironment
CD38
adenosine
Online Access:https://www.mdpi.com/2072-6694/13/2/164

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