Using cluster of differentiation CD 38, CD 45 and CD 95 as a method of primary diagnosis of uterine fibroids

Uterine myoma is one of the first places among gynecological diseases. There is a rise of the number of pathology diagnoses among young women. Currently inUkrainethere is no single approved laboratory method for screening of uterine myomas. The aim of our work is the studying of the efficiency of C...

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Main Authors: I. V. Savytskyi, G. K. Magdenko, I. V. Miastkívska, K. S. Orel, P. E. Grigoriev, L. N. Chernysh
Format: Article
Language:English
Published: Kazimierz Wielki University 2017-07-01
Series:Journal of Education, Health and Sport
Subjects:
Online Access:http://www.ojs.ukw.edu.pl/index.php/johs/article/view/4672
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author I. V. Savytskyi
G. K. Magdenko
I. V. Miastkívska
K. S. Orel
P. E. Grigoriev
L. N. Chernysh
author_facet I. V. Savytskyi
G. K. Magdenko
I. V. Miastkívska
K. S. Orel
P. E. Grigoriev
L. N. Chernysh
author_sort I. V. Savytskyi
collection DOAJ
description Uterine myoma is one of the first places among gynecological diseases. There is a rise of the number of pathology diagnoses among young women. Currently inUkrainethere is no single approved laboratory method for screening of uterine myomas. The aim of our work is the studying of the efficiency of CD38, CD45, and CD95 leukocyte differentiation clusters for early detection of uterine myomas. Determination of a subpopulation of lymphocytes in urine with immune complex of peroxidase-antiperoxidase. The features of the number of leukocytes with CD 38, CD 45, CD 95 antigens were analyzed among women with uterine myoma compared with women who did not have gynecological diseases and underwent an appropriate research. Each sample consisted of 50 women aged 30 to 65 years (average age in both samples was 45 years). The Student's test for independent samples was used for statistical methods of comparison. The results we’ve got indicate that the most statistically significant differences were established by SD 95, so it can be assumed that it is the one that is the most informative as a possible marker for the presence of uterine fibroids. At the same time, during the analyzingof  the clusters of CD38 and CD45 differentiation, there were also found highly significant differences between the group of patients with uterine myoma and healthy women.
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spelling doaj.art-0101e71a4b1c457f8ff793c6a45da8dd2022-12-21T18:12:31ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062017-07-017764665710.5281/zenodo.8395354417Using cluster of differentiation CD 38, CD 45 and CD 95 as a method of primary diagnosis of uterine fibroidsI. V. Savytskyi0G. K. Magdenko1I. V. Miastkívska2K. S. Orel3P. E. Grigoriev4L. N. Chernysh5Odessa national medical universityMykolaiv oncologic DispensaryOdessa national medical universityOdessa Regional HospitalTyumen State UniversityUkrainian scientific research institute of transport medicineUterine myoma is one of the first places among gynecological diseases. There is a rise of the number of pathology diagnoses among young women. Currently inUkrainethere is no single approved laboratory method for screening of uterine myomas. The aim of our work is the studying of the efficiency of CD38, CD45, and CD95 leukocyte differentiation clusters for early detection of uterine myomas. Determination of a subpopulation of lymphocytes in urine with immune complex of peroxidase-antiperoxidase. The features of the number of leukocytes with CD 38, CD 45, CD 95 antigens were analyzed among women with uterine myoma compared with women who did not have gynecological diseases and underwent an appropriate research. Each sample consisted of 50 women aged 30 to 65 years (average age in both samples was 45 years). The Student's test for independent samples was used for statistical methods of comparison. The results we’ve got indicate that the most statistically significant differences were established by SD 95, so it can be assumed that it is the one that is the most informative as a possible marker for the presence of uterine fibroids. At the same time, during the analyzingof  the clusters of CD38 and CD45 differentiation, there were also found highly significant differences between the group of patients with uterine myoma and healthy women.http://www.ojs.ukw.edu.pl/index.php/johs/article/view/4672uterine myoma, cd 38, cd45, cd95, screening method
spellingShingle I. V. Savytskyi
G. K. Magdenko
I. V. Miastkívska
K. S. Orel
P. E. Grigoriev
L. N. Chernysh
Using cluster of differentiation CD 38, CD 45 and CD 95 as a method of primary diagnosis of uterine fibroids
Journal of Education, Health and Sport
uterine myoma, cd 38, cd45, cd95, screening method
title Using cluster of differentiation CD 38, CD 45 and CD 95 as a method of primary diagnosis of uterine fibroids
title_full Using cluster of differentiation CD 38, CD 45 and CD 95 as a method of primary diagnosis of uterine fibroids
title_fullStr Using cluster of differentiation CD 38, CD 45 and CD 95 as a method of primary diagnosis of uterine fibroids
title_full_unstemmed Using cluster of differentiation CD 38, CD 45 and CD 95 as a method of primary diagnosis of uterine fibroids
title_short Using cluster of differentiation CD 38, CD 45 and CD 95 as a method of primary diagnosis of uterine fibroids
title_sort using cluster of differentiation cd 38 cd 45 and cd 95 as a method of primary diagnosis of uterine fibroids
topic uterine myoma, cd 38, cd45, cd95, screening method
url http://www.ojs.ukw.edu.pl/index.php/johs/article/view/4672
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