Pancreatic acinar cell carcinoma with predominant extension into the main pancreatic duct: A case report
Abstract A 34‐year‐old male was referred to our hospital for a possible pancreatic mass detected by computed tomography (CT) that was performed to find the cause of acute pancreatitis. Multiple imaging tests, including contrast‐enhanced CT scan, magnetic resonance imaging, contrast‐enhanced endoscop...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2022-04-01
|
| Series: | DEN Open |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/deo2.96 |
| _version_ | 1811312396920160256 |
|---|---|
| author | Takuya Ishikawa Eizaburo Ohno Yasuyuki Mizutani Tadashi Iida Hiroki Kawashima |
| author_facet | Takuya Ishikawa Eizaburo Ohno Yasuyuki Mizutani Tadashi Iida Hiroki Kawashima |
| author_sort | Takuya Ishikawa |
| collection | DOAJ |
| description | Abstract A 34‐year‐old male was referred to our hospital for a possible pancreatic mass detected by computed tomography (CT) that was performed to find the cause of acute pancreatitis. Multiple imaging tests, including contrast‐enhanced CT scan, magnetic resonance imaging, contrast‐enhanced endoscopic ultrasonography, and endoscopic retrograde pancreatography, revealed a solid mass occupying the head of the main pancreatic duct (MDP), and pancreaticoduodenectomy was performed. In the resected specimen, the tumor showed expansive growth from the pancreatic parenchyma to the MDP and formed a tumor plug. Histopathological findings together with immunostaining findings led to the diagnosis of pancreatic acinar cell carcinoma (PACC). The patient was alive and recurrence‐free for 11 years after surgery. Extension into the MDP is more common in PACC than in conventional pancreatic ductal adenocarcinoma. PACC patients with MDP extension may have less aggressive clinicopathologic characteristics, and a relatively good prognosis can be expected. |
| first_indexed | 2024-04-13T10:36:36Z |
| format | Article |
| id | doaj.art-010311a7942246e686d1c40438877c59 |
| institution | Directory Open Access Journal |
| issn | 2692-4609 |
| language | English |
| last_indexed | 2024-04-13T10:36:36Z |
| publishDate | 2022-04-01 |
| publisher | Wiley |
| record_format | Article |
| series | DEN Open |
| spelling | doaj.art-010311a7942246e686d1c40438877c592022-12-22T02:50:03ZengWileyDEN Open2692-46092022-04-0121n/an/a10.1002/deo2.96Pancreatic acinar cell carcinoma with predominant extension into the main pancreatic duct: A case reportTakuya Ishikawa0Eizaburo Ohno1Yasuyuki Mizutani2Tadashi Iida3Hiroki Kawashima4Department of Gastroenterology and Hepatology Nagoya University Graduate School of Medicine Aichi JapanDepartment of Gastroenterology and Hepatology Nagoya University Graduate School of Medicine Aichi JapanDepartment of Gastroenterology and Hepatology Nagoya University Graduate School of Medicine Aichi JapanDepartment of Gastroenterology and Hepatology Nagoya University Graduate School of Medicine Aichi JapanDepartment of Endoscopy Nagoya University Hospital Aichi JapanAbstract A 34‐year‐old male was referred to our hospital for a possible pancreatic mass detected by computed tomography (CT) that was performed to find the cause of acute pancreatitis. Multiple imaging tests, including contrast‐enhanced CT scan, magnetic resonance imaging, contrast‐enhanced endoscopic ultrasonography, and endoscopic retrograde pancreatography, revealed a solid mass occupying the head of the main pancreatic duct (MDP), and pancreaticoduodenectomy was performed. In the resected specimen, the tumor showed expansive growth from the pancreatic parenchyma to the MDP and formed a tumor plug. Histopathological findings together with immunostaining findings led to the diagnosis of pancreatic acinar cell carcinoma (PACC). The patient was alive and recurrence‐free for 11 years after surgery. Extension into the MDP is more common in PACC than in conventional pancreatic ductal adenocarcinoma. PACC patients with MDP extension may have less aggressive clinicopathologic characteristics, and a relatively good prognosis can be expected.https://doi.org/10.1002/deo2.96contrast‐enhanced endoscopic ultrasonographyendoscopic retrograde pancreatographymain pancreatic ductpancreatic acinar cell carcinomapancreaticoduodenectomy |
| spellingShingle | Takuya Ishikawa Eizaburo Ohno Yasuyuki Mizutani Tadashi Iida Hiroki Kawashima Pancreatic acinar cell carcinoma with predominant extension into the main pancreatic duct: A case report DEN Open contrast‐enhanced endoscopic ultrasonography endoscopic retrograde pancreatography main pancreatic duct pancreatic acinar cell carcinoma pancreaticoduodenectomy |
| title | Pancreatic acinar cell carcinoma with predominant extension into the main pancreatic duct: A case report |
| title_full | Pancreatic acinar cell carcinoma with predominant extension into the main pancreatic duct: A case report |
| title_fullStr | Pancreatic acinar cell carcinoma with predominant extension into the main pancreatic duct: A case report |
| title_full_unstemmed | Pancreatic acinar cell carcinoma with predominant extension into the main pancreatic duct: A case report |
| title_short | Pancreatic acinar cell carcinoma with predominant extension into the main pancreatic duct: A case report |
| title_sort | pancreatic acinar cell carcinoma with predominant extension into the main pancreatic duct a case report |
| topic | contrast‐enhanced endoscopic ultrasonography endoscopic retrograde pancreatography main pancreatic duct pancreatic acinar cell carcinoma pancreaticoduodenectomy |
| url | https://doi.org/10.1002/deo2.96 |
| work_keys_str_mv | AT takuyaishikawa pancreaticacinarcellcarcinomawithpredominantextensionintothemainpancreaticductacasereport AT eizaburoohno pancreaticacinarcellcarcinomawithpredominantextensionintothemainpancreaticductacasereport AT yasuyukimizutani pancreaticacinarcellcarcinomawithpredominantextensionintothemainpancreaticductacasereport AT tadashiiida pancreaticacinarcellcarcinomawithpredominantextensionintothemainpancreaticductacasereport AT hirokikawashima pancreaticacinarcellcarcinomawithpredominantextensionintothemainpancreaticductacasereport |