Physiologically Based Pharmacokinetic Modeling of Nanoparticle Biodistribution: A Review of Existing Models, Simulation Software, and Data Analysis Tools

Physiologically Based Pharmacokinetic Modeling of Nanoparticle Biodistribution: A Review of Existing Models, Simulation Software, and Data Analysis Tools

Cancer treatment and pharmaceutical development require targeted treatment and less toxic therapeutic intervention to achieve real progress against this disease. In this scenario, nanomedicine emerged as a reliable tool to improve drug pharmacokinetics and to translate to the clinical biologics base...

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Bibliographic Details
Main Authors: Elena O. Kutumova, Ilya R. Akberdin, Ilya N. Kiselev, Ruslan N. Sharipov, Vera S. Egorova, Anastasiia O. Syrocheva, Alessandro Parodi, Andrey A. Zamyatnin, Fedor A. Kolpakov
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:International Journal of Molecular Sciences
Subjects:
nanoparticles
physiologically based pharmacokinetic modeling
simulation software
BioUML
Online Access:https://www.mdpi.com/1422-0067/23/20/12560

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