Assisted reproductive technology in Japan: A summary report for 2019 by the Ethics Committee of the Japan Society of Obstetrics and Gynecology

Abstract Purpose The Japan Society of Obstetrics and Gynecology records online annual cycle‐based information for assisted reproductive technology (ART). This report presents the characteristics and treatment outcomes of ART cycles registered during 2019. Methods The Japanese ART registry includes c...

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Main Authors: Yukiko Katagiri, Seung Chik Jwa, Akira Kuwahara, Takeshi Iwasa, Masanori Ono, Keiichi Kato, Hiroshi Kishi, Yoshimitsu Kuwabara, Miyuki Harada, Toshio Hamatani, Yutaka Osuga
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Reproductive Medicine and Biology
Subjects:
Online Access:https://doi.org/10.1002/rmb2.12434
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author Yukiko Katagiri
Seung Chik Jwa
Akira Kuwahara
Takeshi Iwasa
Masanori Ono
Keiichi Kato
Hiroshi Kishi
Yoshimitsu Kuwabara
Miyuki Harada
Toshio Hamatani
Yutaka Osuga
author_facet Yukiko Katagiri
Seung Chik Jwa
Akira Kuwahara
Takeshi Iwasa
Masanori Ono
Keiichi Kato
Hiroshi Kishi
Yoshimitsu Kuwabara
Miyuki Harada
Toshio Hamatani
Yutaka Osuga
author_sort Yukiko Katagiri
collection DOAJ
description Abstract Purpose The Japan Society of Obstetrics and Gynecology records online annual cycle‐based information for assisted reproductive technology (ART). This report presents the characteristics and treatment outcomes of ART cycles registered during 2019. Methods The Japanese ART registry includes cycle‐specific information from 619 participating facilities, including treatment and pregnancy outcomes. Descriptive analyses were conducted for cycles registered during 2019. Results In 2019, 458 101 treatment cycles and 60 598 neonates were reported, both of which increased from 2018. The number of fresh cycles, including in vitro fertilization and intracytoplasmic sperm injection, decreased, while frozen‐thawed embryo transfer (ET) cycles increased. The mean maternal age was 37.9 years (standard deviation ± 4.7). Of 239 348 oocyte retrievals, 123 690 (51.7%) involved freeze‐all‐embryos cycles; fresh ET was performed in 41 831 cycles (a decreasing trend since 2015). In 2019, there were 211 597 frozen‐thawed ET cycles, resulting in 74 882 pregnancies and 54 168 neonates born. Single ET was performed in 82.6% of fresh transfers and 85.1% of frozen‐thawed cycles, with singleton live birth rates of 97.3% for both. Conclusions The number of fresh cycles decreased but frozen cycles increased in 2019. Single ET was performed in >80% of cases, and the proportion of babies born from frozen‐thawed ET increased.
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spelling doaj.art-010c9b1d6956438e84e19d0508cabad42022-12-27T13:54:58ZengWileyReproductive Medicine and Biology1445-57811447-05782022-01-01211n/an/a10.1002/rmb2.12434Assisted reproductive technology in Japan: A summary report for 2019 by the Ethics Committee of the Japan Society of Obstetrics and GynecologyYukiko Katagiri0Seung Chik Jwa1Akira Kuwahara2Takeshi Iwasa3Masanori Ono4Keiichi Kato5Hiroshi Kishi6Yoshimitsu Kuwabara7Miyuki Harada8Toshio Hamatani9Yutaka Osuga10Department of Obstetrics and Gynecology Faculty of Medicine Toho University Tokyo JapanDepartment of Obstetrics and Gynecology Saitama Medical University Saitama JapanDepartment of Obstetrics and Gynecology Graduate School of Biomedical Sciences Tokushima University Tokushima JapanDepartment of Obstetrics and Gynecology Graduate School of Biomedical Sciences Tokushima University Tokushima JapanDepartment of Obstetrics and Gynecology Tokyo Medical University Tokyo JapanKato Ladies Clinic Tokyo JapanDepartment of Obstetrics and Gynecology The Jikei University School of Medicine Tokyo JapanDepartment of Obstetrics and Gynecology Nippon Medical School Tokyo JapanDepartment of Obstetrics and Gynecology Graduate School of Medicine The University of Tokyo Tokyo JapanDepartment of Obstetrics and Gynecology School of Medicine Keio University Tokyo JapanDepartment of Obstetrics and Gynecology Graduate School of Medicine The University of Tokyo Tokyo JapanAbstract Purpose The Japan Society of Obstetrics and Gynecology records online annual cycle‐based information for assisted reproductive technology (ART). This report presents the characteristics and treatment outcomes of ART cycles registered during 2019. Methods The Japanese ART registry includes cycle‐specific information from 619 participating facilities, including treatment and pregnancy outcomes. Descriptive analyses were conducted for cycles registered during 2019. Results In 2019, 458 101 treatment cycles and 60 598 neonates were reported, both of which increased from 2018. The number of fresh cycles, including in vitro fertilization and intracytoplasmic sperm injection, decreased, while frozen‐thawed embryo transfer (ET) cycles increased. The mean maternal age was 37.9 years (standard deviation ± 4.7). Of 239 348 oocyte retrievals, 123 690 (51.7%) involved freeze‐all‐embryos cycles; fresh ET was performed in 41 831 cycles (a decreasing trend since 2015). In 2019, there were 211 597 frozen‐thawed ET cycles, resulting in 74 882 pregnancies and 54 168 neonates born. Single ET was performed in 82.6% of fresh transfers and 85.1% of frozen‐thawed cycles, with singleton live birth rates of 97.3% for both. Conclusions The number of fresh cycles decreased but frozen cycles increased in 2019. Single ET was performed in >80% of cases, and the proportion of babies born from frozen‐thawed ET increased.https://doi.org/10.1002/rmb2.12434assisted reproductive technologycryopreservationintracytoplasmic sperm injectionsJapanregistries
spellingShingle Yukiko Katagiri
Seung Chik Jwa
Akira Kuwahara
Takeshi Iwasa
Masanori Ono
Keiichi Kato
Hiroshi Kishi
Yoshimitsu Kuwabara
Miyuki Harada
Toshio Hamatani
Yutaka Osuga
Assisted reproductive technology in Japan: A summary report for 2019 by the Ethics Committee of the Japan Society of Obstetrics and Gynecology
Reproductive Medicine and Biology
assisted reproductive technology
cryopreservation
intracytoplasmic sperm injections
Japan
registries
title Assisted reproductive technology in Japan: A summary report for 2019 by the Ethics Committee of the Japan Society of Obstetrics and Gynecology
title_full Assisted reproductive technology in Japan: A summary report for 2019 by the Ethics Committee of the Japan Society of Obstetrics and Gynecology
title_fullStr Assisted reproductive technology in Japan: A summary report for 2019 by the Ethics Committee of the Japan Society of Obstetrics and Gynecology
title_full_unstemmed Assisted reproductive technology in Japan: A summary report for 2019 by the Ethics Committee of the Japan Society of Obstetrics and Gynecology
title_short Assisted reproductive technology in Japan: A summary report for 2019 by the Ethics Committee of the Japan Society of Obstetrics and Gynecology
title_sort assisted reproductive technology in japan a summary report for 2019 by the ethics committee of the japan society of obstetrics and gynecology
topic assisted reproductive technology
cryopreservation
intracytoplasmic sperm injections
Japan
registries
url https://doi.org/10.1002/rmb2.12434
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