Role and Limits of COVID-19 Vaccines in the Delicate Transition from Pandemic Mitigation to Endemic Control

The recent surge of COVID-19 related to the Omicron variant emergence has thrown a harsh light upon epidemic control in the near future. This should lead the scientific and medical community to question the long-term vaccine strategy for SARS-CoV-2 control. We provide here a critical point of view r...

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Main Authors: Marie Mura, Fabrice Simon, Vincent Pommier de Santi, Frédéric Tangy, Jean-Nicolas Tournier
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Vaccines
Subjects:
Online Access:https://www.mdpi.com/2076-393X/10/9/1555
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author Marie Mura
Fabrice Simon
Vincent Pommier de Santi
Frédéric Tangy
Jean-Nicolas Tournier
author_facet Marie Mura
Fabrice Simon
Vincent Pommier de Santi
Frédéric Tangy
Jean-Nicolas Tournier
author_sort Marie Mura
collection DOAJ
description The recent surge of COVID-19 related to the Omicron variant emergence has thrown a harsh light upon epidemic control in the near future. This should lead the scientific and medical community to question the long-term vaccine strategy for SARS-CoV-2 control. We provide here a critical point of view regarding the virological evolution, epidemiological aspects, and immunological drivers for COVID-19 control, including a vaccination strategy. Overall, we need more innovations in vaccine development to reduce the COVID-19 burden long term. The most adequate answer might be better cooperation between universities, biotech and pharmaceutical companies
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spelling doaj.art-010f4b62fd684976b701872cf5d8eb8a2023-11-23T19:23:08ZengMDPI AGVaccines2076-393X2022-09-01109155510.3390/vaccines10091555Role and Limits of COVID-19 Vaccines in the Delicate Transition from Pandemic Mitigation to Endemic ControlMarie Mura0Fabrice Simon1Vincent Pommier de Santi2Frédéric Tangy3Jean-Nicolas Tournier4Microbiology and Infectious Diseases Department, Institut de Recherche Biomédicale des Armées (IRBA), 91220 Brétigny sur Orge, FranceDepartment of Infectious Diseases and Tropical Medicine, HIA Laveran, 13384 Marseille, FranceFrench Armed Forces Center for Epidemiology and Public Health (CESPA), 13014 Marseille, FranceInnovative Vaccine Laboratory, Institut Pasteur, 75015 Paris, FranceMicrobiology and Infectious Diseases Department, Institut de Recherche Biomédicale des Armées (IRBA), 91220 Brétigny sur Orge, FranceThe recent surge of COVID-19 related to the Omicron variant emergence has thrown a harsh light upon epidemic control in the near future. This should lead the scientific and medical community to question the long-term vaccine strategy for SARS-CoV-2 control. We provide here a critical point of view regarding the virological evolution, epidemiological aspects, and immunological drivers for COVID-19 control, including a vaccination strategy. Overall, we need more innovations in vaccine development to reduce the COVID-19 burden long term. The most adequate answer might be better cooperation between universities, biotech and pharmaceutical companieshttps://www.mdpi.com/2076-393X/10/9/1555SARS-CoV-2COVID-19vaccinevariantOmicronDelta
spellingShingle Marie Mura
Fabrice Simon
Vincent Pommier de Santi
Frédéric Tangy
Jean-Nicolas Tournier
Role and Limits of COVID-19 Vaccines in the Delicate Transition from Pandemic Mitigation to Endemic Control
Vaccines
SARS-CoV-2
COVID-19
vaccine
variant
Omicron
Delta
title Role and Limits of COVID-19 Vaccines in the Delicate Transition from Pandemic Mitigation to Endemic Control
title_full Role and Limits of COVID-19 Vaccines in the Delicate Transition from Pandemic Mitigation to Endemic Control
title_fullStr Role and Limits of COVID-19 Vaccines in the Delicate Transition from Pandemic Mitigation to Endemic Control
title_full_unstemmed Role and Limits of COVID-19 Vaccines in the Delicate Transition from Pandemic Mitigation to Endemic Control
title_short Role and Limits of COVID-19 Vaccines in the Delicate Transition from Pandemic Mitigation to Endemic Control
title_sort role and limits of covid 19 vaccines in the delicate transition from pandemic mitigation to endemic control
topic SARS-CoV-2
COVID-19
vaccine
variant
Omicron
Delta
url https://www.mdpi.com/2076-393X/10/9/1555
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