A chemically fueled non-enzymatic bistable network
Although bistability is common in biology, it is very difficult to design de novo into synthetic systems. Here, the authors present an experimental and theoretical analysis of a chemical network that displays bistable behavior under certain far-from-equilibrium conditions, and map the parameter spac...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2019-10-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-019-12645-0 |
| _version_ | 1819036074432790528 |
|---|---|
| author | Indrajit Maity Nathaniel Wagner Rakesh Mukherjee Dharm Dev Enrique Peacock-Lopez Rivka Cohen-Luria Gonen Ashkenasy |
| author_facet | Indrajit Maity Nathaniel Wagner Rakesh Mukherjee Dharm Dev Enrique Peacock-Lopez Rivka Cohen-Luria Gonen Ashkenasy |
| author_sort | Indrajit Maity |
| collection | DOAJ |
| description | Although bistability is common in biology, it is very difficult to design de novo into synthetic systems. Here, the authors present an experimental and theoretical analysis of a chemical network that displays bistable behavior under certain far-from-equilibrium conditions, and map the parameter space in which bistability operates. |
| first_indexed | 2024-12-21T07:59:44Z |
| format | Article |
| id | doaj.art-010ffc2c0d79488ba8051e94703a73de |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-21T07:59:44Z |
| publishDate | 2019-10-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-010ffc2c0d79488ba8051e94703a73de2022-12-21T19:10:55ZengNature PortfolioNature Communications2041-17232019-10-011011910.1038/s41467-019-12645-0A chemically fueled non-enzymatic bistable networkIndrajit Maity0Nathaniel Wagner1Rakesh Mukherjee2Dharm Dev3Enrique Peacock-Lopez4Rivka Cohen-Luria5Gonen Ashkenasy6Department of Chemistry, Ben-Gurion University of the NegevDepartment of Chemistry, Ben-Gurion University of the NegevDepartment of Chemistry, Ben-Gurion University of the NegevDepartment of Chemistry, Ben-Gurion University of the NegevDepartment of Chemistry, Williams CollegeDepartment of Chemistry, Ben-Gurion University of the NegevDepartment of Chemistry, Ben-Gurion University of the NegevAlthough bistability is common in biology, it is very difficult to design de novo into synthetic systems. Here, the authors present an experimental and theoretical analysis of a chemical network that displays bistable behavior under certain far-from-equilibrium conditions, and map the parameter space in which bistability operates.https://doi.org/10.1038/s41467-019-12645-0 |
| spellingShingle | Indrajit Maity Nathaniel Wagner Rakesh Mukherjee Dharm Dev Enrique Peacock-Lopez Rivka Cohen-Luria Gonen Ashkenasy A chemically fueled non-enzymatic bistable network Nature Communications |
| title | A chemically fueled non-enzymatic bistable network |
| title_full | A chemically fueled non-enzymatic bistable network |
| title_fullStr | A chemically fueled non-enzymatic bistable network |
| title_full_unstemmed | A chemically fueled non-enzymatic bistable network |
| title_short | A chemically fueled non-enzymatic bistable network |
| title_sort | chemically fueled non enzymatic bistable network |
| url | https://doi.org/10.1038/s41467-019-12645-0 |
| work_keys_str_mv | AT indrajitmaity achemicallyfuelednonenzymaticbistablenetwork AT nathanielwagner achemicallyfuelednonenzymaticbistablenetwork AT rakeshmukherjee achemicallyfuelednonenzymaticbistablenetwork AT dharmdev achemicallyfuelednonenzymaticbistablenetwork AT enriquepeacocklopez achemicallyfuelednonenzymaticbistablenetwork AT rivkacohenluria achemicallyfuelednonenzymaticbistablenetwork AT gonenashkenasy achemicallyfuelednonenzymaticbistablenetwork AT indrajitmaity chemicallyfuelednonenzymaticbistablenetwork AT nathanielwagner chemicallyfuelednonenzymaticbistablenetwork AT rakeshmukherjee chemicallyfuelednonenzymaticbistablenetwork AT dharmdev chemicallyfuelednonenzymaticbistablenetwork AT enriquepeacocklopez chemicallyfuelednonenzymaticbistablenetwork AT rivkacohenluria chemicallyfuelednonenzymaticbistablenetwork AT gonenashkenasy chemicallyfuelednonenzymaticbistablenetwork |