The Use of High-dose Corticosteroids in Seriously Ill Children with Acute Viral Bronchiolitis

Introduction:The aim of the present study is to investigate whether high-dose corticosteroids cause a clinical improvement in seriously ill children with acute viral bronchiolitis.Methods:Hospital records of patients diagnosed with acute viral bronchiolitis and admitted to the pediatric intensive ca...

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Main Author: Çelebi Kocaoğlu
Format: Article
Language:English
Published: Galenos Yayinevi 2020-08-01
Series:Journal of Pediatric Emergency and Intensive Care Medicine
Subjects:
Online Access: http://www.caybdergi.com/archives/archive-detail/article-preview/the-use-of-high-dose-corticosteroids-in-seriously-/38651
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author Çelebi Kocaoğlu
author_facet Çelebi Kocaoğlu
author_sort Çelebi Kocaoğlu
collection DOAJ
description Introduction:The aim of the present study is to investigate whether high-dose corticosteroids cause a clinical improvement in seriously ill children with acute viral bronchiolitis.Methods:Hospital records of patients diagnosed with acute viral bronchiolitis and admitted to the pediatric intensive care unit or general pediatrics service in a tertiary care hospital were reviewed retrospectively. Patients receiving steroids were divided into two subgroups: high-dose and standard-dose corticosteroid recipients. Patients diagnosed with acute viral bronchiolitis but receiving no corticosteroid treatment constituted the control group.Results:While there was no difference between the pre- and post-drug pulse rates of all three groups, a difference was observed in both pre- and post-drug breathing rates between the high-dose steroid and control groups. However, there was no difference between the average pre- and post-drug breathing rates in the high-dose steroid, standard-dose steroid and control groups. There was no regression relationship between the treatment applied and either the pulse rate or the breathing rate in the entire study group.Conclusion:The results of our study show that even at high doses, corticosteroids provide no obvious improvement in the patient's clinical status and do not shorten the length of hospitalisation.
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spelling doaj.art-0110e3ef37f54d1199aaf21a9bf0834b2023-02-15T16:10:03ZengGalenos YayineviJournal of Pediatric Emergency and Intensive Care Medicine2148-73322148-73322020-08-0172697310.4274/cayd.galenos.2019.9248513049054The Use of High-dose Corticosteroids in Seriously Ill Children with Acute Viral BronchiolitisÇelebi Kocaoğlu0 Konya Training and Research Hospital, Clinic of Pediatric Intensive Care, Konya, Turkey Introduction:The aim of the present study is to investigate whether high-dose corticosteroids cause a clinical improvement in seriously ill children with acute viral bronchiolitis.Methods:Hospital records of patients diagnosed with acute viral bronchiolitis and admitted to the pediatric intensive care unit or general pediatrics service in a tertiary care hospital were reviewed retrospectively. Patients receiving steroids were divided into two subgroups: high-dose and standard-dose corticosteroid recipients. Patients diagnosed with acute viral bronchiolitis but receiving no corticosteroid treatment constituted the control group.Results:While there was no difference between the pre- and post-drug pulse rates of all three groups, a difference was observed in both pre- and post-drug breathing rates between the high-dose steroid and control groups. However, there was no difference between the average pre- and post-drug breathing rates in the high-dose steroid, standard-dose steroid and control groups. There was no regression relationship between the treatment applied and either the pulse rate or the breathing rate in the entire study group.Conclusion:The results of our study show that even at high doses, corticosteroids provide no obvious improvement in the patient's clinical status and do not shorten the length of hospitalisation. http://www.caybdergi.com/archives/archive-detail/article-preview/the-use-of-high-dose-corticosteroids-in-seriously-/38651 bronchiolitischildrencorticosteroidhigh-dosetreatment
spellingShingle Çelebi Kocaoğlu
The Use of High-dose Corticosteroids in Seriously Ill Children with Acute Viral Bronchiolitis
Journal of Pediatric Emergency and Intensive Care Medicine
bronchiolitis
children
corticosteroid
high-dose
treatment
title The Use of High-dose Corticosteroids in Seriously Ill Children with Acute Viral Bronchiolitis
title_full The Use of High-dose Corticosteroids in Seriously Ill Children with Acute Viral Bronchiolitis
title_fullStr The Use of High-dose Corticosteroids in Seriously Ill Children with Acute Viral Bronchiolitis
title_full_unstemmed The Use of High-dose Corticosteroids in Seriously Ill Children with Acute Viral Bronchiolitis
title_short The Use of High-dose Corticosteroids in Seriously Ill Children with Acute Viral Bronchiolitis
title_sort use of high dose corticosteroids in seriously ill children with acute viral bronchiolitis
topic bronchiolitis
children
corticosteroid
high-dose
treatment
url http://www.caybdergi.com/archives/archive-detail/article-preview/the-use-of-high-dose-corticosteroids-in-seriously-/38651
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