Myxofibrosarcoma of maxilla: A case report of rare entity
Myxofibrosarcoma is one of the most common sarcomas in the extremities of elderly patients that rarely affect the oral cavity. In this article we describe a case of primary myxofibrosarcoma of maxilla in a 19-year-old boy. Microscopically the tumor showed loosely arranged spindle-shaped tumor cells...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2015-01-01
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| Series: | Journal of Indian Academy of Oral Medicine and Radiology |
| Subjects: | |
| Online Access: | http://www.jiaomr.in/article.asp?issn=0972-1363;year=2015;volume=27;issue=2;spage=294;epage=297;aulast=Nallapu |
| _version_ | 1819074162185994240 |
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| author | Venkateswarlu Nallapu Bhavya Balasankulu Sailaja Sambhana Hima Bindu Vuppalapati |
| author_facet | Venkateswarlu Nallapu Bhavya Balasankulu Sailaja Sambhana Hima Bindu Vuppalapati |
| author_sort | Venkateswarlu Nallapu |
| collection | DOAJ |
| description | Myxofibrosarcoma is one of the most common sarcomas in the extremities of elderly patients that rarely affect the oral cavity. In this article we describe a case of primary myxofibrosarcoma of maxilla in a 19-year-old boy. Microscopically the tumor showed loosely arranged spindle-shaped tumor cells with mild pleomorphic spindle-shaped nuclei, some with minute nucleoli in a fibromyxoid stroma. The cells were strongly immunoreactive for vimentin and negative for CD-68, S-100 protein and desmin. Based on clinical, histological and immunohistochemical findings, a final diagnosis of myxofibrosarcoma was established. It is an unusual aggressive variant that frequently recurs and metastasizes, reinforcing the importance of its correct diagnosis. We report a rare case of myxofibrosarcoma in maxilla, with emphasis on immunohistochemical findings. |
| first_indexed | 2024-12-21T18:05:08Z |
| format | Article |
| id | doaj.art-011188bca93b407580843a3912194264 |
| institution | Directory Open Access Journal |
| issn | 0972-1363 0975-1572 |
| language | English |
| last_indexed | 2024-12-21T18:05:08Z |
| publishDate | 2015-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Indian Academy of Oral Medicine and Radiology |
| spelling | doaj.art-011188bca93b407580843a39121942642022-12-21T18:54:57ZengWolters Kluwer Medknow PublicationsJournal of Indian Academy of Oral Medicine and Radiology0972-13630975-15722015-01-0127229429710.4103/0972-1363.170163Myxofibrosarcoma of maxilla: A case report of rare entityVenkateswarlu NallapuBhavya BalasankuluSailaja SambhanaHima Bindu VuppalapatiMyxofibrosarcoma is one of the most common sarcomas in the extremities of elderly patients that rarely affect the oral cavity. In this article we describe a case of primary myxofibrosarcoma of maxilla in a 19-year-old boy. Microscopically the tumor showed loosely arranged spindle-shaped tumor cells with mild pleomorphic spindle-shaped nuclei, some with minute nucleoli in a fibromyxoid stroma. The cells were strongly immunoreactive for vimentin and negative for CD-68, S-100 protein and desmin. Based on clinical, histological and immunohistochemical findings, a final diagnosis of myxofibrosarcoma was established. It is an unusual aggressive variant that frequently recurs and metastasizes, reinforcing the importance of its correct diagnosis. We report a rare case of myxofibrosarcoma in maxilla, with emphasis on immunohistochemical findings.http://www.jiaomr.in/article.asp?issn=0972-1363;year=2015;volume=27;issue=2;spage=294;epage=297;aulast=NallapuFibrosarcomaimmunohistochemistrymaxillamyxofibrosarcoma |
| spellingShingle | Venkateswarlu Nallapu Bhavya Balasankulu Sailaja Sambhana Hima Bindu Vuppalapati Myxofibrosarcoma of maxilla: A case report of rare entity Journal of Indian Academy of Oral Medicine and Radiology Fibrosarcoma immunohistochemistry maxilla myxofibrosarcoma |
| title | Myxofibrosarcoma of maxilla: A case report of rare entity |
| title_full | Myxofibrosarcoma of maxilla: A case report of rare entity |
| title_fullStr | Myxofibrosarcoma of maxilla: A case report of rare entity |
| title_full_unstemmed | Myxofibrosarcoma of maxilla: A case report of rare entity |
| title_short | Myxofibrosarcoma of maxilla: A case report of rare entity |
| title_sort | myxofibrosarcoma of maxilla a case report of rare entity |
| topic | Fibrosarcoma immunohistochemistry maxilla myxofibrosarcoma |
| url | http://www.jiaomr.in/article.asp?issn=0972-1363;year=2015;volume=27;issue=2;spage=294;epage=297;aulast=Nallapu |
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