Polycystic Ovary Syndrome Susceptibility Loci Inform Disease Etiological Heterogeneity

Polycystic Ovary Syndrome Susceptibility Loci Inform Disease Etiological Heterogeneity

Polycystic ovary syndrome (PCOS) is a complex disorder with heterogenous phenotypes and unclear etiology. A recent phenotypic clustering study identified metabolic and reproductive subtypes of PCOS. We hypothesize that the heterogeneity of PCOS manifestations reflects different mechanistic pathways...

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Bibliographic Details
Main Authors: Yanfei Zhang, Vani C. Movva, Marc S. Williams, Ming Ta Michael Lee
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Journal of Clinical Medicine
Subjects:
polycystic ovary syndrome
clustering
genetic heterogeneity
adiposity
insulin resistance
Mendelian randomization
Online Access:https://www.mdpi.com/2077-0383/10/12/2688

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