Synthesis of Chitosan Oligosaccharide-Loaded Glycyrrhetinic Acid Functionalized Mesoporous Silica Nanoparticles and In Vitro Verification of the Treatment of APAP-Induced Liver Injury

Synthesis of Chitosan Oligosaccharide-Loaded Glycyrrhetinic Acid Functionalized Mesoporous Silica Nanoparticles and In Vitro Verification of the Treatment of APAP-Induced Liver Injury

Objective: the study was to find a suitable treatment for acute drug-induced liver injury. The use of nanocarriers can improve the therapeutic effect of natural drugs by targeting hepatocytes and higher loads. Methods: firstly, uniformly dispersed three-dimensional dendritic mesoporous silica nanosp...

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Bibliographic Details
Main Authors: Xinghua Guo, Chengcheng Zhang, Yan Bai, Qishi Che, Hua Cao, Jiao Guo, Zhengquan Su
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Molecules
Subjects:
acetaminophen
chitosan oligosaccharide
drug-induced liver injury
glycyrrhetinic acid modification
mesoporous silica
Online Access:https://www.mdpi.com/1420-3049/28/10/4147

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https://www.mdpi.com/1420-3049/28/10/4147

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