Comparison of dendritic calcium transients in juvenile wild type and SOD1G93A mouse lumbar motoneurons

Comparison of dendritic calcium transients in juvenile wild type and SOD1G93A mouse lumbar motoneurons

Previous studies of spinal motoneurons in the SOD1 mouse model of amyotrophic lateral sclerosis have shown alterations long before disease onset, including increased dendritic branching, increased persistent Na+ and Ca2+ currents, and impaired axonal transport. In this study dendritic Ca2+ entry was...

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Bibliographic Details
Main Authors: Katharina Ann Quinlan, Jonathan Balquiedra Lamano, Julienne eSamuels, CJ eHeckman
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-04-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Calcium Channels
Motor Neurons
Spinal Cord
dendritic processing
Amyotrophic lateral sclerosis (ALS)
Multiphoton imaging
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00139/full

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