Popliteal lymphadenectomy for treating metastatic melanoma: case report
CONTEXT: Regional lymph node involvement in patients with malignant melanomas has been associated with poor prognosis. In-transit metastases also lead to poor long-term survival. Whereas for nodal disease only regional lymphadenectomy offers adequate locoregional control, for in-transit metastasis b...
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| Format: | Article |
| Language: | English |
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Associação Paulista de Medicina
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| Series: | São Paulo Medical Journal |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802008000400009&lng=en&tlng=en |
| _version_ | 1818999962207256576 |
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| author | Sergio Renato Pais Costa Sergio Henrique Couto Horta Alexandre Cruz Henriques |
| author_facet | Sergio Renato Pais Costa Sergio Henrique Couto Horta Alexandre Cruz Henriques |
| author_sort | Sergio Renato Pais Costa |
| collection | DOAJ |
| description | CONTEXT: Regional lymph node involvement in patients with malignant melanomas has been associated with poor prognosis. In-transit metastases also lead to poor long-term survival. Whereas for nodal disease only regional lymphadenectomy offers adequate locoregional control, for in-transit metastasis both local excision and isolated limb perfusion with chemotherapy plus tumor necrosis factor-alpha can be used for disease control. In cases of tumors located in the distal region of the legs, the lymphatic dissemination most commonly observed is to the inguinal chain. Consequently, therapeutic inguinal lymphadenectomy or even selective lymphadenectomy (sentinel lymph node biopsy) have been recommended. On the other hand, involvement of the popliteal chain is very rare. When this occurs, popliteal lymphadenectomy should be indicated. Local excision may be the logical approach for a few small in-transit metastases because of the low morbidity in this procedure, when compared with isolated limb perfusion. CASE REPORT: A case of melanoma of the heel with popliteal chain involvement and in-transit metastases is presented. This was treated by means of regional lymphadenectomy plus in-transit metastases excision, with a good postoperative course. |
| first_indexed | 2024-12-20T22:25:45Z |
| format | Article |
| id | doaj.art-01165ea12aea40379393ab1b659e4f9b |
| institution | Directory Open Access Journal |
| issn | 1806-9460 |
| language | English |
| last_indexed | 2024-12-20T22:25:45Z |
| publisher | Associação Paulista de Medicina |
| record_format | Article |
| series | São Paulo Medical Journal |
| spelling | doaj.art-01165ea12aea40379393ab1b659e4f9b2022-12-21T19:24:49ZengAssociação Paulista de MedicinaSão Paulo Medical Journal1806-9460126423223510.1590/S1516-31802008000400009S1516-31802008000400009Popliteal lymphadenectomy for treating metastatic melanoma: case reportSergio Renato Pais Costa0Sergio Henrique Couto Horta1Alexandre Cruz Henriques2Faculdade de Medicina do ABCFaculdade de Medicina do ABCFaculdade de Medicina do ABCCONTEXT: Regional lymph node involvement in patients with malignant melanomas has been associated with poor prognosis. In-transit metastases also lead to poor long-term survival. Whereas for nodal disease only regional lymphadenectomy offers adequate locoregional control, for in-transit metastasis both local excision and isolated limb perfusion with chemotherapy plus tumor necrosis factor-alpha can be used for disease control. In cases of tumors located in the distal region of the legs, the lymphatic dissemination most commonly observed is to the inguinal chain. Consequently, therapeutic inguinal lymphadenectomy or even selective lymphadenectomy (sentinel lymph node biopsy) have been recommended. On the other hand, involvement of the popliteal chain is very rare. When this occurs, popliteal lymphadenectomy should be indicated. Local excision may be the logical approach for a few small in-transit metastases because of the low morbidity in this procedure, when compared with isolated limb perfusion. CASE REPORT: A case of melanoma of the heel with popliteal chain involvement and in-transit metastases is presented. This was treated by means of regional lymphadenectomy plus in-transit metastases excision, with a good postoperative course.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802008000400009&lng=en&tlng=enMelanomaLymphatic metastasisLymphadenectomySkin neoplasmsLower extremity |
| spellingShingle | Sergio Renato Pais Costa Sergio Henrique Couto Horta Alexandre Cruz Henriques Popliteal lymphadenectomy for treating metastatic melanoma: case report São Paulo Medical Journal Melanoma Lymphatic metastasis Lymphadenectomy Skin neoplasms Lower extremity |
| title | Popliteal lymphadenectomy for treating metastatic melanoma: case report |
| title_full | Popliteal lymphadenectomy for treating metastatic melanoma: case report |
| title_fullStr | Popliteal lymphadenectomy for treating metastatic melanoma: case report |
| title_full_unstemmed | Popliteal lymphadenectomy for treating metastatic melanoma: case report |
| title_short | Popliteal lymphadenectomy for treating metastatic melanoma: case report |
| title_sort | popliteal lymphadenectomy for treating metastatic melanoma case report |
| topic | Melanoma Lymphatic metastasis Lymphadenectomy Skin neoplasms Lower extremity |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802008000400009&lng=en&tlng=en |
| work_keys_str_mv | AT sergiorenatopaiscosta popliteallymphadenectomyfortreatingmetastaticmelanomacasereport AT sergiohenriquecoutohorta popliteallymphadenectomyfortreatingmetastaticmelanomacasereport AT alexandrecruzhenriques popliteallymphadenectomyfortreatingmetastaticmelanomacasereport |