Allelic heterogeneity and trade-off shape natural variation for response to soil micronutrient.
As sessile organisms, plants have to cope with diverse environmental constraints that may vary through time and space, eventually leading to changes in the phenotype of populations through fixation of adaptive genetic variation. To fully comprehend the mechanisms of evolution and make sense of the e...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2012-01-01
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| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC3395621?pdf=render |
| _version_ | 1828530117043814400 |
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| author | Seifollah Poormohammad Kiani Charlotte Trontin Matthew Andreatta Matthieu Simon Thierry Robert David E Salt Olivier Loudet |
| author_facet | Seifollah Poormohammad Kiani Charlotte Trontin Matthew Andreatta Matthieu Simon Thierry Robert David E Salt Olivier Loudet |
| author_sort | Seifollah Poormohammad Kiani |
| collection | DOAJ |
| description | As sessile organisms, plants have to cope with diverse environmental constraints that may vary through time and space, eventually leading to changes in the phenotype of populations through fixation of adaptive genetic variation. To fully comprehend the mechanisms of evolution and make sense of the extensive genotypic diversity currently revealed by new sequencing technologies, we are challenged with identifying the molecular basis of such adaptive variation. Here, we have identified a new variant of a molybdenum (Mo) transporter, MOT1, which is causal for fitness changes under artificial conditions of both Mo-deficiency and Mo-toxicity and in which allelic variation among West-Asian populations is strictly correlated with the concentration of available Mo in native soils. In addition, this association is accompanied at different scales with patterns of polymorphisms that are not consistent with neutral evolution and show signs of diversifying selection. Resolving such a case of allelic heterogeneity helps explain species-wide phenotypic variation for Mo homeostasis and potentially reveals trade-off effects, a finding still rarely linked to fitness. |
| first_indexed | 2024-12-11T22:18:35Z |
| format | Article |
| id | doaj.art-0117909dfd554b629743d9031950c7a9 |
| institution | Directory Open Access Journal |
| issn | 1553-7390 1553-7404 |
| language | English |
| last_indexed | 2024-12-11T22:18:35Z |
| publishDate | 2012-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS Genetics |
| spelling | doaj.art-0117909dfd554b629743d9031950c7a92022-12-22T00:48:31ZengPublic Library of Science (PLoS)PLoS Genetics1553-73901553-74042012-01-0187e100281410.1371/journal.pgen.1002814Allelic heterogeneity and trade-off shape natural variation for response to soil micronutrient.Seifollah Poormohammad KianiCharlotte TrontinMatthew AndreattaMatthieu SimonThierry RobertDavid E SaltOlivier LoudetAs sessile organisms, plants have to cope with diverse environmental constraints that may vary through time and space, eventually leading to changes in the phenotype of populations through fixation of adaptive genetic variation. To fully comprehend the mechanisms of evolution and make sense of the extensive genotypic diversity currently revealed by new sequencing technologies, we are challenged with identifying the molecular basis of such adaptive variation. Here, we have identified a new variant of a molybdenum (Mo) transporter, MOT1, which is causal for fitness changes under artificial conditions of both Mo-deficiency and Mo-toxicity and in which allelic variation among West-Asian populations is strictly correlated with the concentration of available Mo in native soils. In addition, this association is accompanied at different scales with patterns of polymorphisms that are not consistent with neutral evolution and show signs of diversifying selection. Resolving such a case of allelic heterogeneity helps explain species-wide phenotypic variation for Mo homeostasis and potentially reveals trade-off effects, a finding still rarely linked to fitness.http://europepmc.org/articles/PMC3395621?pdf=render |
| spellingShingle | Seifollah Poormohammad Kiani Charlotte Trontin Matthew Andreatta Matthieu Simon Thierry Robert David E Salt Olivier Loudet Allelic heterogeneity and trade-off shape natural variation for response to soil micronutrient. PLoS Genetics |
| title | Allelic heterogeneity and trade-off shape natural variation for response to soil micronutrient. |
| title_full | Allelic heterogeneity and trade-off shape natural variation for response to soil micronutrient. |
| title_fullStr | Allelic heterogeneity and trade-off shape natural variation for response to soil micronutrient. |
| title_full_unstemmed | Allelic heterogeneity and trade-off shape natural variation for response to soil micronutrient. |
| title_short | Allelic heterogeneity and trade-off shape natural variation for response to soil micronutrient. |
| title_sort | allelic heterogeneity and trade off shape natural variation for response to soil micronutrient |
| url | http://europepmc.org/articles/PMC3395621?pdf=render |
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