All-atom molecular dynamics of the HBV capsid reveals insights into biological function and cryo-EM resolution limits
The hepatitis B virus capsid represents a promising therapeutic target. Experiments suggest the capsid must be flexible to function; however, capsid structure and dynamics have not been thoroughly characterized in the absence of icosahedral symmetry constraints. Here, all-atom molecular dynamics sim...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2018-04-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/32478 |