The rGel/BLyS Fusion Toxin Inhibits Diffuse Large B-cell Lymphoma Growth In Vitro and In Vivo

Diffuse large B-cell lymphoma (DLBCL) is an aggressive subtype of B-cell non-Hodgkin lymphoma (NHL) and accounts for 30%to 40%of NHL. Molecules targeting nuclear factor-κB (NF-κB) are expected to be of therapeutic value in those tumors where NF-κB seems to play a unique survival role such as activat...

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Hlavní autoři: Mi-Ae Lyu, Deepak Rai, Kwang Seok Ahn, Bokyung Sung, Lawrence H. Cheung, John W. Marks, Bharat B. Aggarwal, Ricardo C.T. Aguiar, Varsha Gandhi, Michael G. Rosenblum
Médium: Článek
Jazyk:English
Vydáno: Elsevier 2010-05-01
Edice:Neoplasia: An International Journal for Oncology Research
On-line přístup:http://www.sciencedirect.com/science/article/pii/S1476558610800545