Ginsenoside Rg3 induces apoptosis and inhibits proliferation by down-regulating TIGAR in rats with gastric precancerous lesions

Ginsenoside Rg3 induces apoptosis and inhibits proliferation by down-regulating TIGAR in rats with gastric precancerous lesions

Abstract Background Ginsenoside Rg3 (GRg3) is one of the main active ingredients in Chinese ginseng extract and has various biological effects, such as immune-enhancing, antitumour, antiangiogenic, immunomodulatory and anti-inflammatory effects. This study aimed to investigate the therapeutic effect...

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Bibliographic Details
Main Authors: Shangbin Lv, Xiaodong Chen, Yu Chen, Daoyin Gong, Gang Mao, Caifei Shen, Ting Xia, Jing Cheng, Zhaoliang Luo, Yu Cheng, Weihong Li, Jinhao Zeng
Format: Article
Language:English
Published: BMC 2022-07-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Ginsenoside Rg3
Gastric precancerous lesions
Apoptosis
TP53-induced glycolysis and apoptosis regulator
Reactive oxygen species
Online Access:https://doi.org/10.1186/s12906-022-03669-z

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