Antibiotic resistance: still a cause of concern?

Abstract. Antibiotic resistance remains a global public health concern with significant patient morbidity and tremendous associated health care costs. Drivers of antibiotic resistance are multifaceted and differ between developing and developed countries. Under evolutionary pressure, microbes acquir...

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Main Authors: Malcolm R. DeBaun, MD, Cara Lai, BS, Mark Sanchez, BS, Michael J. Chen, MD, L. Henry Goodnough, MD, PhD, Amy Chang, MD, Julius A. Bishop, MD, Michael J. Gardner, MD
Format: Article
Language:English
Published: Wolters Kluwer 2021-06-01
Series:OTA International
Online Access:http://journals.lww.com/10.1097/OI9.0000000000000104
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author Malcolm R. DeBaun, MD
Cara Lai, BS
Mark Sanchez, BS
Michael J. Chen, MD
L. Henry Goodnough, MD, PhD
Amy Chang, MD
Julius A. Bishop, MD
Michael J. Gardner, MD
author_facet Malcolm R. DeBaun, MD
Cara Lai, BS
Mark Sanchez, BS
Michael J. Chen, MD
L. Henry Goodnough, MD, PhD
Amy Chang, MD
Julius A. Bishop, MD
Michael J. Gardner, MD
author_sort Malcolm R. DeBaun, MD
collection DOAJ
description Abstract. Antibiotic resistance remains a global public health concern with significant patient morbidity and tremendous associated health care costs. Drivers of antibiotic resistance are multifaceted and differ between developing and developed countries. Under evolutionary pressure, microbes acquire antibiotic tolerance through a variety of mechanisms at the cellular level. Patients after orthopaedic trauma are vulnerable to drug-resistant pathogens, particularly after open fractures. Traumatologists practicing appropriate antibiotic prophylaxis and treatment regimens mitigate infection and propagation of antibiotic resistance.
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spelling doaj.art-01241ddb51d1435a8ded6de7f7fe06bb2023-08-30T06:17:13ZengWolters KluwerOTA International2574-21672021-06-0143Se10410.1097/OI9.0000000000000104OI90000000000000104Antibiotic resistance: still a cause of concern?Malcolm R. DeBaun, MDCara Lai, BSMark Sanchez, BSMichael J. Chen, MDL. Henry Goodnough, MD, PhDAmy Chang, MDJulius A. Bishop, MDMichael J. Gardner, MDAbstract. Antibiotic resistance remains a global public health concern with significant patient morbidity and tremendous associated health care costs. Drivers of antibiotic resistance are multifaceted and differ between developing and developed countries. Under evolutionary pressure, microbes acquire antibiotic tolerance through a variety of mechanisms at the cellular level. Patients after orthopaedic trauma are vulnerable to drug-resistant pathogens, particularly after open fractures. Traumatologists practicing appropriate antibiotic prophylaxis and treatment regimens mitigate infection and propagation of antibiotic resistance.http://journals.lww.com/10.1097/OI9.0000000000000104
spellingShingle Malcolm R. DeBaun, MD
Cara Lai, BS
Mark Sanchez, BS
Michael J. Chen, MD
L. Henry Goodnough, MD, PhD
Amy Chang, MD
Julius A. Bishop, MD
Michael J. Gardner, MD
Antibiotic resistance: still a cause of concern?
OTA International
title Antibiotic resistance: still a cause of concern?
title_full Antibiotic resistance: still a cause of concern?
title_fullStr Antibiotic resistance: still a cause of concern?
title_full_unstemmed Antibiotic resistance: still a cause of concern?
title_short Antibiotic resistance: still a cause of concern?
title_sort antibiotic resistance still a cause of concern
url http://journals.lww.com/10.1097/OI9.0000000000000104
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