Antibiotic resistance: still a cause of concern?
Abstract. Antibiotic resistance remains a global public health concern with significant patient morbidity and tremendous associated health care costs. Drivers of antibiotic resistance are multifaceted and differ between developing and developed countries. Under evolutionary pressure, microbes acquir...
Main Authors: | , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Wolters Kluwer
2021-06-01
|
Series: | OTA International |
Online Access: | http://journals.lww.com/10.1097/OI9.0000000000000104 |
_version_ | 1797732699411054592 |
---|---|
author | Malcolm R. DeBaun, MD Cara Lai, BS Mark Sanchez, BS Michael J. Chen, MD L. Henry Goodnough, MD, PhD Amy Chang, MD Julius A. Bishop, MD Michael J. Gardner, MD |
author_facet | Malcolm R. DeBaun, MD Cara Lai, BS Mark Sanchez, BS Michael J. Chen, MD L. Henry Goodnough, MD, PhD Amy Chang, MD Julius A. Bishop, MD Michael J. Gardner, MD |
author_sort | Malcolm R. DeBaun, MD |
collection | DOAJ |
description | Abstract. Antibiotic resistance remains a global public health concern with significant patient morbidity and tremendous associated health care costs. Drivers of antibiotic resistance are multifaceted and differ between developing and developed countries. Under evolutionary pressure, microbes acquire antibiotic tolerance through a variety of mechanisms at the cellular level. Patients after orthopaedic trauma are vulnerable to drug-resistant pathogens, particularly after open fractures. Traumatologists practicing appropriate antibiotic prophylaxis and treatment regimens mitigate infection and propagation of antibiotic resistance. |
first_indexed | 2024-03-12T12:18:18Z |
format | Article |
id | doaj.art-01241ddb51d1435a8ded6de7f7fe06bb |
institution | Directory Open Access Journal |
issn | 2574-2167 |
language | English |
last_indexed | 2024-03-12T12:18:18Z |
publishDate | 2021-06-01 |
publisher | Wolters Kluwer |
record_format | Article |
series | OTA International |
spelling | doaj.art-01241ddb51d1435a8ded6de7f7fe06bb2023-08-30T06:17:13ZengWolters KluwerOTA International2574-21672021-06-0143Se10410.1097/OI9.0000000000000104OI90000000000000104Antibiotic resistance: still a cause of concern?Malcolm R. DeBaun, MDCara Lai, BSMark Sanchez, BSMichael J. Chen, MDL. Henry Goodnough, MD, PhDAmy Chang, MDJulius A. Bishop, MDMichael J. Gardner, MDAbstract. Antibiotic resistance remains a global public health concern with significant patient morbidity and tremendous associated health care costs. Drivers of antibiotic resistance are multifaceted and differ between developing and developed countries. Under evolutionary pressure, microbes acquire antibiotic tolerance through a variety of mechanisms at the cellular level. Patients after orthopaedic trauma are vulnerable to drug-resistant pathogens, particularly after open fractures. Traumatologists practicing appropriate antibiotic prophylaxis and treatment regimens mitigate infection and propagation of antibiotic resistance.http://journals.lww.com/10.1097/OI9.0000000000000104 |
spellingShingle | Malcolm R. DeBaun, MD Cara Lai, BS Mark Sanchez, BS Michael J. Chen, MD L. Henry Goodnough, MD, PhD Amy Chang, MD Julius A. Bishop, MD Michael J. Gardner, MD Antibiotic resistance: still a cause of concern? OTA International |
title | Antibiotic resistance: still a cause of concern? |
title_full | Antibiotic resistance: still a cause of concern? |
title_fullStr | Antibiotic resistance: still a cause of concern? |
title_full_unstemmed | Antibiotic resistance: still a cause of concern? |
title_short | Antibiotic resistance: still a cause of concern? |
title_sort | antibiotic resistance still a cause of concern |
url | http://journals.lww.com/10.1097/OI9.0000000000000104 |
work_keys_str_mv | AT malcolmrdebaunmd antibioticresistancestillacauseofconcern AT caralaibs antibioticresistancestillacauseofconcern AT marksanchezbs antibioticresistancestillacauseofconcern AT michaeljchenmd antibioticresistancestillacauseofconcern AT lhenrygoodnoughmdphd antibioticresistancestillacauseofconcern AT amychangmd antibioticresistancestillacauseofconcern AT juliusabishopmd antibioticresistancestillacauseofconcern AT michaeljgardnermd antibioticresistancestillacauseofconcern |