Comparison of three different self-expanding metal stents using rabbit models for the treatment of tracheal collapse

ABSTRACT Purpose: To identify an optimal self-expandable metallic stent (SEMS) and verify whether a mechanically superior SEMS would result in better clinical outcomes in the treatment of tracheal collapse. Methods: We selected three SEMS (n = 8 each), including an S-type stent with a wire diamete...

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Main Authors: Ji-Hyun Kim, Jin-Young Choi, Hun-Young Yoon
Format: Article
Language:English
Published: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2022-08-01
Series:Acta Cirúrgica Brasileira
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502022000500202&tlng=en
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author Ji-Hyun Kim
Jin-Young Choi
Hun-Young Yoon
author_facet Ji-Hyun Kim
Jin-Young Choi
Hun-Young Yoon
author_sort Ji-Hyun Kim
collection DOAJ
description ABSTRACT Purpose: To identify an optimal self-expandable metallic stent (SEMS) and verify whether a mechanically superior SEMS would result in better clinical outcomes in the treatment of tracheal collapse. Methods: We selected three SEMS (n = 8 each), including an S-type stent with a wire diameter of 0.006 inches (S6) and two D-type stents with wire diameters of 0.006 (D6) and 0.007 inches (D7). Twenty-four New Zealand White rabbits were divided into three equal groups. After the stents were deployed, the clinical signs were recorded daily, and radiographic examinations were performed monthly. All rabbits were euthanized after three months. Results: Two rabbits with S6 stents and one rabbit with a D7 stent died within three months because of stent migration or pneumonia. All rabbits with D6 stents survived for three months. On histological examination, the D6 group had the lowest inflammation score. Conclusions: Both clinically and histopathologically, the results with D-type stents with a wire diameter of 0.006 inches were superior to those of the other groups (p = 0.001). The use of an optimal intraluminal stent may improve the long-term clinical outcomes in the treatment of tracheal collapse in dogs.
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spelling doaj.art-012b01586dc942e0b8ef65d39a4a820d2022-12-22T03:44:23ZengSociedade Brasileira para o Desenvolvimento da Pesquisa em CirurgiaActa Cirúrgica Brasileira1678-26742022-08-0137510.1590/acb370502Comparison of three different self-expanding metal stents using rabbit models for the treatment of tracheal collapseJi-Hyun Kimhttps://orcid.org/0000-0002-5047-0102Jin-Young Choihttps://orcid.org/0000-0002-6493-2857Hun-Young Yoonhttps://orcid.org/0000-0001-8834-952XABSTRACT Purpose: To identify an optimal self-expandable metallic stent (SEMS) and verify whether a mechanically superior SEMS would result in better clinical outcomes in the treatment of tracheal collapse. Methods: We selected three SEMS (n = 8 each), including an S-type stent with a wire diameter of 0.006 inches (S6) and two D-type stents with wire diameters of 0.006 (D6) and 0.007 inches (D7). Twenty-four New Zealand White rabbits were divided into three equal groups. After the stents were deployed, the clinical signs were recorded daily, and radiographic examinations were performed monthly. All rabbits were euthanized after three months. Results: Two rabbits with S6 stents and one rabbit with a D7 stent died within three months because of stent migration or pneumonia. All rabbits with D6 stents survived for three months. On histological examination, the D6 group had the lowest inflammation score. Conclusions: Both clinically and histopathologically, the results with D-type stents with a wire diameter of 0.006 inches were superior to those of the other groups (p = 0.001). The use of an optimal intraluminal stent may improve the long-term clinical outcomes in the treatment of tracheal collapse in dogs.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502022000500202&tlng=enSelf Expandable Metallic StentsTracheaRabbits
spellingShingle Ji-Hyun Kim
Jin-Young Choi
Hun-Young Yoon
Comparison of three different self-expanding metal stents using rabbit models for the treatment of tracheal collapse
Acta Cirúrgica Brasileira
Self Expandable Metallic Stents
Trachea
Rabbits
title Comparison of three different self-expanding metal stents using rabbit models for the treatment of tracheal collapse
title_full Comparison of three different self-expanding metal stents using rabbit models for the treatment of tracheal collapse
title_fullStr Comparison of three different self-expanding metal stents using rabbit models for the treatment of tracheal collapse
title_full_unstemmed Comparison of three different self-expanding metal stents using rabbit models for the treatment of tracheal collapse
title_short Comparison of three different self-expanding metal stents using rabbit models for the treatment of tracheal collapse
title_sort comparison of three different self expanding metal stents using rabbit models for the treatment of tracheal collapse
topic Self Expandable Metallic Stents
Trachea
Rabbits
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502022000500202&tlng=en
work_keys_str_mv AT jihyunkim comparisonofthreedifferentselfexpandingmetalstentsusingrabbitmodelsforthetreatmentoftrachealcollapse
AT jinyoungchoi comparisonofthreedifferentselfexpandingmetalstentsusingrabbitmodelsforthetreatmentoftrachealcollapse
AT hunyoungyoon comparisonofthreedifferentselfexpandingmetalstentsusingrabbitmodelsforthetreatmentoftrachealcollapse