Integrating digital pathology and mathematical modelling to predict spatial biomarker dynamics in cancer immunotherapy

Abstract In oncology clinical trials, on-treatment biopsy samples are taken to confirm the mode of action of new molecules, among other reasons. Yet, the time point of sample collection is typically scheduled according to 'Expert Best Guess'. We have developed an approach integrating digit...

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Bibliographic Details
Main Authors: L. G. Hutchinson, O. Grimm
Format: Article
Language:English
Published: Nature Portfolio 2022-07-01
Series:npj Digital Medicine
Online Access:https://doi.org/10.1038/s41746-022-00636-3

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