Multiple sclerosis, visual evoked potentials, cooling effect, Uhthoff’s phenomenon
Objective: Multiple sclerosis (MS) is a chronic demyelinating disease of the central nervous system that principally affects young adults. Recent studies from different parts of the world have shown that the incidence and prevalence of MS is increasing each year. No data are available on this subjec...
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Format: | Article |
Language: | English |
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Galenos Yayinevi
2021-03-01
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Series: | Türk Nöroloji Dergisi |
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Online Access: | https://tjn.org.tr/jvi.aspx?pdir=tjn&plng=eng&un=TJN-36418&look4= |
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author | Cem Bölük Ülkü Türk Börü Mustafa Taşdemir Tuğçe Gezer |
author_facet | Cem Bölük Ülkü Türk Börü Mustafa Taşdemir Tuğçe Gezer |
author_sort | Cem Bölük |
collection | DOAJ |
description | Objective: Multiple sclerosis (MS) is a chronic demyelinating disease of the central nervous system that principally affects young adults. Recent studies from different parts of the world have shown that the incidence and prevalence of MS is increasing each year. No data are available on this subject for Turkey. With this study, we aimed to evaluate the 10-year trend of MS prevalence in two rural cities of Turkey for the first time.
Materials and Methods: The study was designed as a cross-sectional, community-based, descriptive epidemiologic study. Geyve and Kandıra districts were screened using a validated questionnaire between 2016-2017. During the field study, all suspected participants were invited to a public health center for reexamination along with their laboratory and imaging findings. Local state hospitals were used to complete this process if required and diagnosis was then confirmed. The revised McDonald 2010 criteria were used in diagnosing MS. Results were compared with a previous study that was conducted 10 years prior by the same team using an identical methodology.
Results: Seventeen thousand one hundred people were screened in Geyve and 12,120 people were screened in Kandıra. Ten people were diagnosed as having MS in Geyve and four were diagnosed in Kandıra. The total prevalence was found as 47.9/100,000. The female/male ratio was 2.5. Nine patients had relapsing remitting MS, four had secondary progressive MS, and one patient had primary progressive MS. When compared with the previous study, the age-standardized prevalence was not statistically different (49.6/100,000; 48.5/100,000 p=0.955).
Conclusion: The results of this study indicate that the prevalence of MS is not increasing in two rural cities in Turkey. |
first_indexed | 2024-04-10T10:29:26Z |
format | Article |
id | doaj.art-0130bb61627d485789d92c214432d573 |
institution | Directory Open Access Journal |
issn | 1309-2545 |
language | English |
last_indexed | 2024-04-10T10:29:26Z |
publishDate | 2021-03-01 |
publisher | Galenos Yayinevi |
record_format | Article |
series | Türk Nöroloji Dergisi |
spelling | doaj.art-0130bb61627d485789d92c214432d5732023-02-15T16:21:10ZengGalenos YayineviTürk Nöroloji Dergisi1309-25452021-03-01271414510.4274/tnd.2020.36418Multiple sclerosis, visual evoked potentials, cooling effect, Uhthoff’s phenomenonCem Bölük0https://orcid.org/0000-0003-0125-7660Ülkü Türk Börü1https://orcid.org/0000-0002-0094-5624Mustafa Taşdemir2https://orcid.org/0000-0002-3148-1981Tuğçe Gezer3https://orcid.org/0000-0002-3167-1822Istanbul University-Cerrahpasa, Cerrahpasa Faculty of Medicine, Department of Neurology, Istanbul, TurkeyAfyonkarahisar University of Health Sciences, Department of Neurology, Afyon, TurkeyIstanbul Medeniyet University, Department of Public Health, Istanbul, TurkeyUniversity of Health Sciences Turkey, Dr. Kartal Lutfi Kirdar City Hospital, Clinic of Neurology, Istanbul, TurkeyObjective: Multiple sclerosis (MS) is a chronic demyelinating disease of the central nervous system that principally affects young adults. Recent studies from different parts of the world have shown that the incidence and prevalence of MS is increasing each year. No data are available on this subject for Turkey. With this study, we aimed to evaluate the 10-year trend of MS prevalence in two rural cities of Turkey for the first time. Materials and Methods: The study was designed as a cross-sectional, community-based, descriptive epidemiologic study. Geyve and Kandıra districts were screened using a validated questionnaire between 2016-2017. During the field study, all suspected participants were invited to a public health center for reexamination along with their laboratory and imaging findings. Local state hospitals were used to complete this process if required and diagnosis was then confirmed. The revised McDonald 2010 criteria were used in diagnosing MS. Results were compared with a previous study that was conducted 10 years prior by the same team using an identical methodology. Results: Seventeen thousand one hundred people were screened in Geyve and 12,120 people were screened in Kandıra. Ten people were diagnosed as having MS in Geyve and four were diagnosed in Kandıra. The total prevalence was found as 47.9/100,000. The female/male ratio was 2.5. Nine patients had relapsing remitting MS, four had secondary progressive MS, and one patient had primary progressive MS. When compared with the previous study, the age-standardized prevalence was not statistically different (49.6/100,000; 48.5/100,000 p=0.955). Conclusion: The results of this study indicate that the prevalence of MS is not increasing in two rural cities in Turkey.https://tjn.org.tr/jvi.aspx?pdir=tjn&plng=eng&un=TJN-36418&look4=population-based studyepidemiologymultiple sclerosisprevalencerural citiesturkey |
spellingShingle | Cem Bölük Ülkü Türk Börü Mustafa Taşdemir Tuğçe Gezer Multiple sclerosis, visual evoked potentials, cooling effect, Uhthoff’s phenomenon Türk Nöroloji Dergisi population-based study epidemiology multiple sclerosis prevalence rural cities turkey |
title | Multiple sclerosis, visual evoked potentials, cooling effect, Uhthoff’s phenomenon |
title_full | Multiple sclerosis, visual evoked potentials, cooling effect, Uhthoff’s phenomenon |
title_fullStr | Multiple sclerosis, visual evoked potentials, cooling effect, Uhthoff’s phenomenon |
title_full_unstemmed | Multiple sclerosis, visual evoked potentials, cooling effect, Uhthoff’s phenomenon |
title_short | Multiple sclerosis, visual evoked potentials, cooling effect, Uhthoff’s phenomenon |
title_sort | multiple sclerosis visual evoked potentials cooling effect uhthoff s phenomenon |
topic | population-based study epidemiology multiple sclerosis prevalence rural cities turkey |
url | https://tjn.org.tr/jvi.aspx?pdir=tjn&plng=eng&un=TJN-36418&look4= |
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