IGF-1 rs6218 polymorphisms modulate the susceptibility to age-related cataract

Background Single nucleotide polymorphisms (SNPs), as the most abundant form of DNA variation in the human genome, contribute to age-related cataracts (ARC) development. Apoptosis of lens epithelial cells (LECs) is closely related to ARC formation. Insulin-like growth factor 1 (IGF1) contributes to...

Full description

Bibliographic Details
Main Authors: Xi Zou, Jun Zhang, Yong Wang, Dong Zhou, Guohua Deng, Zhinan Liu
Format: Article
Language:English
Published: PeerJ Inc. 2024-04-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/17220.pdf