Chemical approaches to discover the full potential of peptide nucleic acids in biomedical applications

Peptide nucleic acid (PNA) is arguably one of the most successful DNA mimics, despite a most dramatic departure from the native structure of DNA. The present review summarizes 30 years of research on PNA’s chemistry, optimization of structure and function, applications as probes and diagnostics, and...

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Bibliographic Details
Main Authors: Nikita Brodyagin, Martins Katkevics, Venubabu Kotikam, Christopher A. Ryan, Eriks Rozners
Format: Article
Language:English
Published: Beilstein-Institut 2021-07-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.17.116