The frequency of CCR5 promoter polymorphisms and CCR5 32 mutation in Iranian populations

The frequency of CCR5 promoter polymorphisms and CCR5 32 mutation in Iranian populations

Evidence showed that chemokines serve as pro-migratory factors for immune cells. CCL3, CCL4 and CCL5, as the main CC  chemokines subfamily members, activate immune cells through binding to CC chemokine receptor 5 or CCR5. Macrophages, NK cells and T lymphocytes express CCR5 and thus, affected CCR5 e...

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Bibliographic Details
Main Authors: Mohammad Zare-Bidaki, Masoud Karimi-Googheri, Gholamhossein Hassanshahi, Nahid Zainodini, Mohammad Kazemi Arababadi
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2015-04-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
CCR5
32 mutation
Polymorphism
Iran
Online Access:http://ijbms.mums.ac.ir/pdf_4278_29d40ed5f135e3a7d405db47b6caf413.html

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