Bronchiolitis, epidemiological changes during the SARS-CoV-2 pandemic
Abstract Background Bronchiolitis is the most common viral infection of the lower respiratory tract in infants under 2 years of age. The aim of this study was to analyze and compare the seasonal bronchiolitis peaks before and during the SARS-CoV-2 pandemic. Methods Descriptive, prospective, and obse...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2022-01-01
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| Series: | BMC Infectious Diseases |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12879-022-07041-x |
| _version_ | 1818940172734038016 |
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| author | Carmina Guitart Sara Bobillo-Perez Carme Alejandre Georgina Armero Cristian Launes Francisco Jose Cambra Monica Balaguer Iolanda Jordan Hospital Network for R. S. V. surveillance in Catalonia |
| author_facet | Carmina Guitart Sara Bobillo-Perez Carme Alejandre Georgina Armero Cristian Launes Francisco Jose Cambra Monica Balaguer Iolanda Jordan Hospital Network for R. S. V. surveillance in Catalonia |
| author_sort | Carmina Guitart |
| collection | DOAJ |
| description | Abstract Background Bronchiolitis is the most common viral infection of the lower respiratory tract in infants under 2 years of age. The aim of this study was to analyze and compare the seasonal bronchiolitis peaks before and during the SARS-CoV-2 pandemic. Methods Descriptive, prospective, and observational study. Patients with severe bronchiolitis admitted to the Pediatric Intensive Care Unit (PICU) of a referral tertiary hospital between September 2010 and June 2021 were included. Demographic data were collected. Viral laboratory-confirmation was carried out. Each season was analyzed and compared. The daily average temperature was collected. Results 1116 patients were recruited, 58.2% of them males. The median age was 49 days. Respiratory syncytial virus (RSV) was isolated in 782 cases (70.1%). In April 2021, the first and only case of bronchiolitis caused by SARS-CoV-2 was identified. The pre- and post-pandemic periods were compared. There were statistically significant differences regarding: age, 47 vs. 73 days (p = 0.006), PICU and hospital length of stay (p = 0.024 and p = 0.001, respectively), and etiology (p = 0.031). The peak for bronchiolitis in 2020 was non-existent before week 52. A delayed peak was seen around week 26/2021. The mean temperature during the epidemic peak was 10ºC for the years of the last decade and is 23ºC for the present season. Conclusion The COVID-19 pandemic outbreak has led to a clearly observable epidemiological change regarding acute bronchiolitis, which should be studied in detail. The influence of the environmental temperature does not seem to determine the viral circulation. |
| first_indexed | 2024-12-20T06:35:25Z |
| format | Article |
| id | doaj.art-0139db544ff6453297be5a1d186addd7 |
| institution | Directory Open Access Journal |
| issn | 1471-2334 |
| language | English |
| last_indexed | 2024-12-20T06:35:25Z |
| publishDate | 2022-01-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Infectious Diseases |
| spelling | doaj.art-0139db544ff6453297be5a1d186addd72022-12-21T19:50:01ZengBMCBMC Infectious Diseases1471-23342022-01-012211910.1186/s12879-022-07041-xBronchiolitis, epidemiological changes during the SARS-CoV-2 pandemicCarmina Guitart0Sara Bobillo-Perez1Carme Alejandre2Georgina Armero3Cristian Launes4Francisco Jose Cambra5Monica Balaguer6Iolanda Jordan7Hospital Network for R. S. V. surveillance in CataloniaPediatric Intensive Care Unit. Hospital Sant Joan de Déu, University of BarcelonaPediatric Intensive Care Unit. Hospital Sant Joan de Déu, University of BarcelonaPediatric Intensive Care Unit. Hospital Sant Joan de Déu, University of BarcelonaDepartment of Pediatrics, Hospital Sant Joan de Déu, University of BarcelonaDepartment of Pediatrics, Hospital Sant Joan de Déu, University of BarcelonaPediatric Intensive Care Unit. Hospital Sant Joan de Déu, University of BarcelonaPediatric Intensive Care Unit. Hospital Sant Joan de Déu, University of BarcelonaPediatric Intensive Care Unit. Hospital Sant Joan de Déu, University of BarcelonaAbstract Background Bronchiolitis is the most common viral infection of the lower respiratory tract in infants under 2 years of age. The aim of this study was to analyze and compare the seasonal bronchiolitis peaks before and during the SARS-CoV-2 pandemic. Methods Descriptive, prospective, and observational study. Patients with severe bronchiolitis admitted to the Pediatric Intensive Care Unit (PICU) of a referral tertiary hospital between September 2010 and June 2021 were included. Demographic data were collected. Viral laboratory-confirmation was carried out. Each season was analyzed and compared. The daily average temperature was collected. Results 1116 patients were recruited, 58.2% of them males. The median age was 49 days. Respiratory syncytial virus (RSV) was isolated in 782 cases (70.1%). In April 2021, the first and only case of bronchiolitis caused by SARS-CoV-2 was identified. The pre- and post-pandemic periods were compared. There were statistically significant differences regarding: age, 47 vs. 73 days (p = 0.006), PICU and hospital length of stay (p = 0.024 and p = 0.001, respectively), and etiology (p = 0.031). The peak for bronchiolitis in 2020 was non-existent before week 52. A delayed peak was seen around week 26/2021. The mean temperature during the epidemic peak was 10ºC for the years of the last decade and is 23ºC for the present season. Conclusion The COVID-19 pandemic outbreak has led to a clearly observable epidemiological change regarding acute bronchiolitis, which should be studied in detail. The influence of the environmental temperature does not seem to determine the viral circulation.https://doi.org/10.1186/s12879-022-07041-xBronchiolitisSARS-CoV-2PandemicNon-pharmaceutical interventions (NPIs) |
| spellingShingle | Carmina Guitart Sara Bobillo-Perez Carme Alejandre Georgina Armero Cristian Launes Francisco Jose Cambra Monica Balaguer Iolanda Jordan Hospital Network for R. S. V. surveillance in Catalonia Bronchiolitis, epidemiological changes during the SARS-CoV-2 pandemic BMC Infectious Diseases Bronchiolitis SARS-CoV-2 Pandemic Non-pharmaceutical interventions (NPIs) |
| title | Bronchiolitis, epidemiological changes during the SARS-CoV-2 pandemic |
| title_full | Bronchiolitis, epidemiological changes during the SARS-CoV-2 pandemic |
| title_fullStr | Bronchiolitis, epidemiological changes during the SARS-CoV-2 pandemic |
| title_full_unstemmed | Bronchiolitis, epidemiological changes during the SARS-CoV-2 pandemic |
| title_short | Bronchiolitis, epidemiological changes during the SARS-CoV-2 pandemic |
| title_sort | bronchiolitis epidemiological changes during the sars cov 2 pandemic |
| topic | Bronchiolitis SARS-CoV-2 Pandemic Non-pharmaceutical interventions (NPIs) |
| url | https://doi.org/10.1186/s12879-022-07041-x |
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