Ag-polymorphism as cytogenetic a marker of risk of development somatic of a pathology

The aim of the investigation is the study of the regularity of the phenotypic manifestation of the transcriptional activity of the nucleus-forming chromosome regions on the level of the basic proteins of erythrocyte cell membranes as a cytogenetic marker of some predisposition to the arterial hypert...

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Main Authors: I N Medvedev, I V Amelina
Format: Article
Language:English
Published: Peoples’ Friendship University of Russia (RUDN University) 2009-09-01
Series:RUDN Journal of Ecology and Life Safety
Subjects:
Online Access:https://journals.rudn.ru/ecology/article/viewFile/12669/12099
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author I N Medvedev
I V Amelina
author_facet I N Medvedev
I V Amelina
author_sort I N Medvedev
collection DOAJ
description The aim of the investigation is the study of the regularity of the phenotypic manifestation of the transcriptional activity of the nucleus-forming chromosome regions on the level of the basic proteins of erythrocyte cell membranes as a cytogenetic marker of some predisposition to the arterial hypertonia. The comparative analysis of patients with arterial hypertonia and those predisposed to it demonstrated for certain a less 10АgЯОР activity in comparison with the remaining population, conditioning a less active erythrocyte membrane protein synthesis in them, than that in the remaining individuals, which contributes considerably to the arterial hypertonia development. This allows us to regard the 10АgЯОР level as a cytogenetic marker of predisposition and further development of the arterial hypertonia in a human being.
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spelling doaj.art-013e09540ed5415d97d84e1836f8fd7f2022-12-22T03:33:57ZengPeoples’ Friendship University of Russia (RUDN University)RUDN Journal of Ecology and Life Safety2313-23102408-89192009-09-01039510012668Ag-polymorphism as cytogenetic a marker of risk of development somatic of a pathologyI N Medvedev0I V Amelina1Kursk Institute of social education(branch of the institute RSSU (Russian State Social University))Kursk Institute of social education(branch of the institute RSSU (Russian State Social University))The aim of the investigation is the study of the regularity of the phenotypic manifestation of the transcriptional activity of the nucleus-forming chromosome regions on the level of the basic proteins of erythrocyte cell membranes as a cytogenetic marker of some predisposition to the arterial hypertonia. The comparative analysis of patients with arterial hypertonia and those predisposed to it demonstrated for certain a less 10АgЯОР activity in comparison with the remaining population, conditioning a less active erythrocyte membrane protein synthesis in them, than that in the remaining individuals, which contributes considerably to the arterial hypertonia development. This allows us to regard the 10АgЯОР level as a cytogenetic marker of predisposition and further development of the arterial hypertonia in a human being.https://journals.rudn.ru/ecology/article/viewFile/12669/12099somatometric indicesag-polymorphismnucleus organizing regionscytogenetic marker
spellingShingle I N Medvedev
I V Amelina
Ag-polymorphism as cytogenetic a marker of risk of development somatic of a pathology
RUDN Journal of Ecology and Life Safety
somatometric indices
ag-polymorphism
nucleus organizing regions
cytogenetic marker
title Ag-polymorphism as cytogenetic a marker of risk of development somatic of a pathology
title_full Ag-polymorphism as cytogenetic a marker of risk of development somatic of a pathology
title_fullStr Ag-polymorphism as cytogenetic a marker of risk of development somatic of a pathology
title_full_unstemmed Ag-polymorphism as cytogenetic a marker of risk of development somatic of a pathology
title_short Ag-polymorphism as cytogenetic a marker of risk of development somatic of a pathology
title_sort ag polymorphism as cytogenetic a marker of risk of development somatic of a pathology
topic somatometric indices
ag-polymorphism
nucleus organizing regions
cytogenetic marker
url https://journals.rudn.ru/ecology/article/viewFile/12669/12099
work_keys_str_mv AT inmedvedev agpolymorphismascytogeneticamarkerofriskofdevelopmentsomaticofapathology
AT ivamelina agpolymorphismascytogeneticamarkerofriskofdevelopmentsomaticofapathology