Vitamin D receptor-deficient keratinocytes-derived exosomal miR-4505 promotes the macrophage polarization towards the M1 phenotype

Background The vitamin D receptor (VDR) has a low level of expression in the keratinocytes of patients with psoriasis and plays a role in the development of the disease. Furthermore, the crosstalk between macrophages and psoriatic keratinocytes-derived exosomes is critical for psoriasis progression....

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Bibliographic Details
Main Authors: Wen Sun, Jianqin Chen, Jingting Li, Xiaoguang She, Hu Ma, Shali Wang, Jing Liu, Yuan Yuan
Format: Article
Language:English
Published: PeerJ Inc. 2023-08-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/15798.pdf