Vitamin D receptor-deficient keratinocytes-derived exosomal miR-4505 promotes the macrophage polarization towards the M1 phenotype
Background The vitamin D receptor (VDR) has a low level of expression in the keratinocytes of patients with psoriasis and plays a role in the development of the disease. Furthermore, the crosstalk between macrophages and psoriatic keratinocytes-derived exosomes is critical for psoriasis progression....
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2023-08-01
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Series: | PeerJ |
Subjects: | |
Online Access: | https://peerj.com/articles/15798.pdf |