Association of Functional Gastrointestinal Disorders with Adolescent Idiopathic Scoliosis
Numerous adolescents diagnosed with adolescent idiopathic scoliosis (AIS) often manifest symptoms indicative of functional gastrointestinal disorders (FGIDs). However, the precise connection between FGIDs and AIS remains unclear. The study involved adolescents drawn from sample datasets provided by...
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-01-01
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| Series: | Children |
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| Online Access: | https://www.mdpi.com/2227-9067/11/1/118 |
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| author | Soo-Bin Lee Hyun-Wook Chae Ji-Won Kwon Sahyun Sung Seong-Hwan Moon Kyung-Soo Suk Hak-Sun Kim Si-Young Park Byung Ho Lee |
| author_facet | Soo-Bin Lee Hyun-Wook Chae Ji-Won Kwon Sahyun Sung Seong-Hwan Moon Kyung-Soo Suk Hak-Sun Kim Si-Young Park Byung Ho Lee |
| author_sort | Soo-Bin Lee |
| collection | DOAJ |
| description | Numerous adolescents diagnosed with adolescent idiopathic scoliosis (AIS) often manifest symptoms indicative of functional gastrointestinal disorders (FGIDs). However, the precise connection between FGIDs and AIS remains unclear. The study involved adolescents drawn from sample datasets provided by the Korean Health Insurance Review and Assessment Service spanning from 2012 to 2016, with a median dataset size of 1,446,632 patients. The AIS group consisted of individuals aged 10 to 19 with diagnostic codes for AIS, while the control group consisted of those without AIS diagnostic codes. The median prevalence of FGIDs in adolescents with AIS from 2012 to 2016 was 24%. When accounting for confounding factors, the analysis revealed that adolescents with AIS were consistently more prone to experiencing FGIDs each year (2012: adjusted odds ratio (aOR), 1.21 [95% confidence interval (CI), 1.10–1.35], <i>p</i> < 0.001; 2013: aOR, 1.31 [95% CI, 1.18–1.46], <i>p</i> < 0.001; 2014: aOR, 1.24 [95% CI, 1.12–1.38], <i>p</i> < 0.001; 2015: aOR, 1.34 [95% CI, 1.21–1.49], <i>p</i> < 0.001; and 2016: aOR, 1.35 [95% CI, 1.21–1.50], <i>p</i> < 0.001). These findings suggest that AIS is correlated with an elevated likelihood of FGIDs, indicating that AIS may function as a potential risk factor for these gastrointestinal issues. Consequently, it is recommended to provide counseling to adolescents with AIS, alerting them to the heightened probability of experiencing chronic gastrointestinal symptoms. |
| first_indexed | 2024-03-08T11:00:44Z |
| format | Article |
| id | doaj.art-013e6fa1c1d948f68ea2c6fc02d37836 |
| institution | Directory Open Access Journal |
| issn | 2227-9067 |
| language | English |
| last_indexed | 2024-03-08T11:00:44Z |
| publishDate | 2024-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Children |
| spelling | doaj.art-013e6fa1c1d948f68ea2c6fc02d378362024-01-26T15:49:34ZengMDPI AGChildren2227-90672024-01-0111111810.3390/children11010118Association of Functional Gastrointestinal Disorders with Adolescent Idiopathic ScoliosisSoo-Bin Lee0Hyun-Wook Chae1Ji-Won Kwon2Sahyun Sung3Seong-Hwan Moon4Kyung-Soo Suk5Hak-Sun Kim6Si-Young Park7Byung Ho Lee8Department of Orthopedic Surgery, Catholic Kwandong University International St. Mary’s Hospital, Incheon 22711, Republic of KoreaDepartment of Pediatrics, Yonsei University College of Medicine, Seoul 03722, Republic of KoreaDepartment of Orthopedic Surgery, Yonsei University College of Medicine, Seoul 03722, Republic of KoreaDepartment of Orthopedic Surgery, Ewha Womans University Seoul Hospital, Seoul 07804, Republic of KoreaDepartment of Orthopedic Surgery, Yonsei University College of Medicine, Seoul 03722, Republic of KoreaDepartment of Orthopedic Surgery, Yonsei University College of Medicine, Seoul 03722, Republic of KoreaDepartment of Orthopedic Surgery, Yonsei University College of Medicine, Seoul 03722, Republic of KoreaDepartment of Orthopedic Surgery, Yonsei University College of Medicine, Seoul 03722, Republic of KoreaDepartment of Orthopedic Surgery, Yonsei University College of Medicine, Seoul 03722, Republic of KoreaNumerous adolescents diagnosed with adolescent idiopathic scoliosis (AIS) often manifest symptoms indicative of functional gastrointestinal disorders (FGIDs). However, the precise connection between FGIDs and AIS remains unclear. The study involved adolescents drawn from sample datasets provided by the Korean Health Insurance Review and Assessment Service spanning from 2012 to 2016, with a median dataset size of 1,446,632 patients. The AIS group consisted of individuals aged 10 to 19 with diagnostic codes for AIS, while the control group consisted of those without AIS diagnostic codes. The median prevalence of FGIDs in adolescents with AIS from 2012 to 2016 was 24%. When accounting for confounding factors, the analysis revealed that adolescents with AIS were consistently more prone to experiencing FGIDs each year (2012: adjusted odds ratio (aOR), 1.21 [95% confidence interval (CI), 1.10–1.35], <i>p</i> < 0.001; 2013: aOR, 1.31 [95% CI, 1.18–1.46], <i>p</i> < 0.001; 2014: aOR, 1.24 [95% CI, 1.12–1.38], <i>p</i> < 0.001; 2015: aOR, 1.34 [95% CI, 1.21–1.49], <i>p</i> < 0.001; and 2016: aOR, 1.35 [95% CI, 1.21–1.50], <i>p</i> < 0.001). These findings suggest that AIS is correlated with an elevated likelihood of FGIDs, indicating that AIS may function as a potential risk factor for these gastrointestinal issues. Consequently, it is recommended to provide counseling to adolescents with AIS, alerting them to the heightened probability of experiencing chronic gastrointestinal symptoms.https://www.mdpi.com/2227-9067/11/1/118functional gastrointestinal disorderidiopathic scoliosisfunctional dyspepsiairritable bowel syndrome |
| spellingShingle | Soo-Bin Lee Hyun-Wook Chae Ji-Won Kwon Sahyun Sung Seong-Hwan Moon Kyung-Soo Suk Hak-Sun Kim Si-Young Park Byung Ho Lee Association of Functional Gastrointestinal Disorders with Adolescent Idiopathic Scoliosis Children functional gastrointestinal disorder idiopathic scoliosis functional dyspepsia irritable bowel syndrome |
| title | Association of Functional Gastrointestinal Disorders with Adolescent Idiopathic Scoliosis |
| title_full | Association of Functional Gastrointestinal Disorders with Adolescent Idiopathic Scoliosis |
| title_fullStr | Association of Functional Gastrointestinal Disorders with Adolescent Idiopathic Scoliosis |
| title_full_unstemmed | Association of Functional Gastrointestinal Disorders with Adolescent Idiopathic Scoliosis |
| title_short | Association of Functional Gastrointestinal Disorders with Adolescent Idiopathic Scoliosis |
| title_sort | association of functional gastrointestinal disorders with adolescent idiopathic scoliosis |
| topic | functional gastrointestinal disorder idiopathic scoliosis functional dyspepsia irritable bowel syndrome |
| url | https://www.mdpi.com/2227-9067/11/1/118 |
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