Combined treatments with AZD5363, AZD8542, curcumin or resveratrol induce death of human glioblastoma cells by suppressing the PI3K/AKT and SHH signaling pathways

Combined treatments with AZD5363, AZD8542, curcumin or resveratrol induce death of human glioblastoma cells by suppressing the PI3K/AKT and SHH signaling pathways

Glioblastoma (GBM) is a very aggressive tumor that presents vascularization, necrosis and is resistant to chemotherapy and radiotherapy. Current treatments are not effective eradicating GBM, thus, there is an urgent need to develop novel therapeutic strategies against GBM. AZD5363, AZD8542, curcumin...

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Bibliographic Details
Main Authors: Rosalinda Mejía-Rodríguez, Daniel Romero-Trejo, Rosa O. González, José Segovia
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Biochemistry and Biophysics Reports
Subjects:
Glioma
Combined therapy
Resveratrol
Curcumin
AZD5363
AZD8542
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580823000110

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