Rosiglitazone attenuates the metalloprotease/anti-metalloprotease imbalance in emphysema induced by cigarette smoke: involvement of extracellular signal-regulated kinase and NFκB signaling

Gang Hou, Yan Yin, Dan Han, Qiu-yue Wang, Jian Kang Department of Respiratory Medicine, the First Hospital of China Medical University, Shenyang, People’s Republic of China Objective: We investigated how rosiglitazone attenuated cigarette smoke (CS)-induced emphysema in a rat model. In p...

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Bibliographic Details
Main Authors: Hou G, Yin Y, Han D, Wang QY, Kang J
Format: Article
Language:English
Published: Dove Medical Press 2015-04-01
Series:International Journal of COPD
Online Access:http://www.dovepress.com/rosiglitazone-attenuates-the-metalloproteaseanti-metalloprotease-imbal-peer-reviewed-article-COPD