The Mechanism of Dynamic Interaction between Doxorubicin and Calf Thymus DNA at the Single-Molecule Level Based on Confocal Raman Spectroscopy

The Mechanism of Dynamic Interaction between Doxorubicin and Calf Thymus DNA at the Single-Molecule Level Based on Confocal Raman Spectroscopy

It is of great fundamental significance and practical application to understand the binding sites and dynamic process of the interaction between doxorubicin (DOX) and DNA molecules. Based on the Confocal Raman spectroscopy, the interaction between DOX and calf thymus DNA has been systemically invest...

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Bibliographic Details
Main Authors: Ruihong Zhang, Jie Zhu, Dan Sun, Jie Li, Lina Yao, Shuangshuang Meng, Yan Li, Yang Dang, Kaige Wang
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Micromachines
Subjects:
doxorubicin
calf thymus DNA
binding site
dynamic process
Confocal Raman spectroscopy
Online Access:https://www.mdpi.com/2072-666X/13/6/940

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